Suppr超能文献

酶抑制与激活的数据分析视角,第1部分:三维K'm V'I坐标系在酶抑制与激活数据分析中的应用

Perspectives of data analysis of enzyme inhibition and activation, Part 1: Use of the three-dimensional K'm V'I coordinate system for data analysis of enzyme inhibition and activation.

作者信息

Krupyanko Vladimir I

机构信息

G. K. Skryabin Institute of Biochemistry and Physiology of Microorganisms, Russian Academy of Sciences, Pushchino, Russia.

出版信息

J Biochem Mol Toxicol. 2009 Mar-Apr;23(2):97-100. doi: 10.1002/jbt.20273.

Abstract

The possibility of construction of the three-dimensional (unfolded and folded) K'm V'I rectangular coordinate systems convenient for vector representation of inhibited and activated enzymatic reactions as well as of a two-dimensional K'm V' scalar rectangular coordinate system convenient for diagrammatic representation of enzymatic reactions is considered. The perspectives of using the properties of the three-dimensional L vectors and their scalar L projections for data analysis of enzyme inhibition and activation are analyzed.

摘要

考虑构建三维(展开和折叠)K'm V'I直角坐标系以方便对抑制和激活的酶促反应进行矢量表示,以及构建二维K'm V'标量直角坐标系以方便对酶促反应进行图表表示的可能性。分析了利用三维L向量及其标量L投影的性质进行酶抑制和激活数据分析的前景。

相似文献

8
Mechanistic basis of enzyme-targeted drugs.酶靶向药物的作用机制基础。
Biochemistry. 2005 Apr 19;44(15):5561-71. doi: 10.1021/bi050247e.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验