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酶抑制与激活的数据分析视角,第1部分:三维K'm V'I坐标系在酶抑制与激活数据分析中的应用

Perspectives of data analysis of enzyme inhibition and activation, Part 1: Use of the three-dimensional K'm V'I coordinate system for data analysis of enzyme inhibition and activation.

作者信息

Krupyanko Vladimir I

机构信息

G. K. Skryabin Institute of Biochemistry and Physiology of Microorganisms, Russian Academy of Sciences, Pushchino, Russia.

出版信息

J Biochem Mol Toxicol. 2009 Mar-Apr;23(2):97-100. doi: 10.1002/jbt.20273.

DOI:10.1002/jbt.20273
PMID:19367642
Abstract

The possibility of construction of the three-dimensional (unfolded and folded) K'm V'I rectangular coordinate systems convenient for vector representation of inhibited and activated enzymatic reactions as well as of a two-dimensional K'm V' scalar rectangular coordinate system convenient for diagrammatic representation of enzymatic reactions is considered. The perspectives of using the properties of the three-dimensional L vectors and their scalar L projections for data analysis of enzyme inhibition and activation are analyzed.

摘要

考虑构建三维(展开和折叠)K'm V'I直角坐标系以方便对抑制和激活的酶促反应进行矢量表示,以及构建二维K'm V'标量直角坐标系以方便对酶促反应进行图表表示的可能性。分析了利用三维L向量及其标量L投影的性质进行酶抑制和激活数据分析的前景。

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