Krupyanko V I
Skryabin Institute of Biochemistry and Physiology of Microorganisms, Russian Academy of Sciences, pr. Nauki 5, 142290 Pushchino, Moscow Region, , Russia.
Biochemistry (Mosc). 2007 Apr;72(4):380-91. doi: 10.1134/s0006297907040049.
Equations for calculation of the constants of biparametrical types of enzyme inhibition and activation were obtained that take into account a ratio of the lengths of L vector projections representing such reactions in the three-dimensional K (m)V I coordinate system. This allows higher accuracy of calculation and is more correct for comparison of these constants. Examples of data analysis of enzyme inhibition and activation by using the traditional equations (they do not take into account the lengths of vector projections) and corrected ones (they take into account the lengths of vector projections) are given. The corrected and traditional equations are used for calculation of the constants of biparametrical types of enzyme inhibition and activation.
得到了双参数类型酶抑制和激活常数的计算方程，该方程考虑了在三维K(m)VI坐标系中表示此类反应的L向量投影长度的比率。这使得计算精度更高，并且在比较这些常数时更准确。给出了使用传统方程（未考虑向量投影长度）和修正方程（考虑了向量投影长度）对酶抑制和激活进行数据分析的示例。修正方程和传统方程用于计算双参数类型酶抑制和激活的常数。
