Wilson I R, Oxner R B, Frampton C M, Tisch G, Chapman B A, Cook H B
Department of Gastroenterology, Christchurch Hospital, New Zealand.
Gastrointest Endosc. 1991 Sep-Oct;37(5):527-30. doi: 10.1016/s0016-5107(91)70821-3.
Endoscopic biopsy is an accepted technique for obtaining samples of small bowel mucosa for histological examination. In this study a comparison between endoscopic forceps biopsies and capsule biopsies in estimating disaccharidase enzyme activity in the small bowel was evaluated. Disaccharidase levels on 168 consecutive small bowel biopsies obtained by either endoscopic biopsy or capsule biopsy were reviewed retrospectively. There was no significant difference in enzyme activity in samples collected by either method. Another 18 patients had simultaneous endoscopic and capsule biopsies from the second part of the duodenum. Again, there was no difference in enzyme activity between samples collected by either technique at the same level in the duodenum. The disaccharidase activity in forceps biopsies taken from the second part of the duodenum is equivalent to those obtained by capsule biopsy.
内镜活检是获取小肠黏膜样本进行组织学检查的一种公认技术。在本研究中，评估了内镜钳取活检和胶囊活检在估计小肠双糖酶活性方面的差异。回顾性分析了通过内镜活检或胶囊活检获取的168例连续小肠活检样本的双糖酶水平。两种方法采集的样本中酶活性无显著差异。另外18例患者同时进行了十二指肠第二部的内镜活检和胶囊活检。同样，在十二指肠同一水平，两种技术采集的样本之间酶活性也无差异。从十二指肠第二部钳取的活检样本中的双糖酶活性与通过胶囊活检获得的样本相当。
