环境烟草烟雾及其对哮喘儿童症状和药物治疗的影响。

Environmental tobacco smoke and its effect on the symptoms and medication in children with asthma.

作者信息

Yamasaki Akira, Hanaki Keichi, Tomita Katsuyuki, Watanabe Masanari, Hasagawa Yasuyuki, Okazaki Ryota, Igishi Tadashi, Horimukai Kenta, Fukutani Kouji, Sugimoto Yuji, Yamamoto Mitsunobu, Kato Kazuhiro, Ikeda Toshikazu, Konishi Tatsuya, Tokuyasu Hirokazu, Yajima Hiroki, Sejima Hitoshi, Isobe Takeshi, Shimizu Eiji

机构信息

Third Department of Internal Medicine, University of Tottori, Japan.

出版信息

Int J Environ Health Res. 2009 Apr;19(2):97-108. doi: 10.1080/09603120802392884.

DOI:10.1080/09603120802392884

PMID:19370461

Abstract

Environmental tobacco smoke (ETS) worsens asthmatic symptoms. We analyzed the relationship between levels of ETS and asthmatic symptoms and medication. We asked parents of 282 asthmatic children about the general condition, smoke exposure and medication. Patients were classified into three groups: no-ETS (no smoking), mild-ETS (smoking in the house but not in the same room as patient), and heavy-ETS (smoking in the same room as patient). We classified 116 children in no-ETS group, 124 children in mild-ETS group and 42 children in heavy-ETS group. The symptoms were worst and prevalence of leukotriene receptor antagonist and long-acting beta(2)-agonist use were highest in heavy-ETS group. However, there was no statistical difference between no-ETS and mild-ETS groups in prevalence of anti-asthmatic drug use and symptoms. We conclude that a smoking ban in rooms used by asthmatic children is an easy way to reduce ETS, asthmatic symptoms and the use of anti-asthmatic drugs.

摘要

环境烟草烟雾（ETS）会加重哮喘症状。我们分析了ETS水平与哮喘症状及药物治疗之间的关系。我们向282名哮喘儿童的家长询问了孩子的一般情况、烟雾暴露情况及药物治疗情况。患者被分为三组：无ETS组（无烟环境）、轻度ETS组（家中有人吸烟，但不在患者同一房间）和重度ETS组（在患者同一房间吸烟）。我们将116名儿童归入无ETS组，124名儿童归入轻度ETS组，42名儿童归入重度ETS组。重度ETS组的症状最严重，白三烯受体拮抗剂和长效β₂受体激动剂的使用比例最高。然而，无ETS组和轻度ETS组在抗哮喘药物使用情况及症状方面无统计学差异。我们得出结论，在哮喘儿童使用的房间内实施禁烟是减少ETS、哮喘症状及抗哮喘药物使用的简便方法。