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双膦酸盐相关颌骨坏死的影像学表现

Imaging findings in bisphosphonate-related osteonecrosis of jaws.

作者信息

Arce Kevin, Assael Leon A, Weissman Jane L, Markiewicz Michael R

机构信息

Department of Oral and Maxillofacial Surgery, Oregon Health and Science University, Portland, OR 97239, USA. 97239

出版信息

J Oral Maxillofac Surg. 2009 May;67(5 Suppl):75-84. doi: 10.1016/j.joms.2008.12.002.

Abstract

PURPOSE

Bisphosphonate-related osteonecrosis of the jaws (BRONJ) is a well-described clinical condition with consistent radiographic findings. The purpose of this report was to review these findings in an attempt to offer important diagnostic, prognostic, and therapeutic information associated with BRONJ.

MATERIALS AND METHODS

The findings of studies assessing the radiographic landmarks on plain films, intraoral films, orthopantograph, computed tomography, magnetic resonance imaging, and nuclear bone scans in patients with BRONJ were analyzed.

RESULTS

The radiographic findings in patients with BRONJ include osteosclerosis, osteolysis, dense woven bone, a thickened lamina dura, subperiosteal bone deposition, and failure of postsurgical remodeling.

CONCLUSIONS

Consistent imaging findings are noted in the BRONJ patient. Imaging is an essential part of the clinical assessment of the BRONJ patient and might be an additional tool for tracking the progression of the disease.

摘要

目的

双膦酸盐相关颌骨坏死(BRONJ)是一种有详细描述且影像学表现一致的临床病症。本报告旨在回顾这些表现,以期提供与BRONJ相关的重要诊断、预后及治疗信息。

材料与方法

分析了评估BRONJ患者的平片、口腔内片、全景片、计算机断层扫描、磁共振成像及核骨扫描等影像学标志的研究结果。

结果

BRONJ患者的影像学表现包括骨质硬化、骨质溶解、致密编织骨、硬骨板增厚、骨膜下骨沉积及术后重塑失败。

结论

BRONJ患者存在一致的影像学表现。影像学检查是BRONJ患者临床评估的重要组成部分,可能是追踪疾病进展的辅助工具。

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