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锥形束计算机断层扫描(CBCT)在颌骨药物相关性骨坏死(MRONJ)诊断及临床管理中的作用

The Role of Cone Beam Computed Tomography (CBCT) in the Diagnosis and Clinical Management of Medication-Related Osteonecrosis of the Jaw (MRONJ).

作者信息

Ko Yui Yin, Yang Wei-Fa, Leung Yiu Yan

机构信息

Oral and Maxillofacial Surgery, Faculty of Dentistry, The University of Hong Kong, Hong Kong SAR, China.

出版信息

Diagnostics (Basel). 2024 Aug 6;14(16):1700. doi: 10.3390/diagnostics14161700.

Abstract

Medication-related osteonecrosis of the jaw (MRONJ) is a debilitating condition associated with antiresorptive and antiangiogenic medications that are frequently used in treating osteoporosis and cancers. With the ability to produce high-resolution images with a lower radiation dose, cone beam computed tomography (CBCT) is an emerging technology in maxillofacial imaging that offers several advantages in evaluating MRONJ. This review aims to summarise the radiological features of MRONJ as observed via CBCT and highlight its advantages over two-dimensional plain films in assessing MRONJ. CBCT has the capability to detect early MRONJ lesions, characterise the extent and nature of lesions, distinguish MRONJ from other osseous pathologies, and assist in treatment planning. By leveraging the advantages of CBCT, clinicians can enhance their understanding of MRONJ, improve decision making, and ultimately optimize patient care.

摘要

药物相关性颌骨坏死(MRONJ)是一种与抗吸收和抗血管生成药物相关的衰弱性疾病,这些药物常用于治疗骨质疏松症和癌症。锥形束计算机断层扫描(CBCT)能够以较低的辐射剂量产生高分辨率图像,是颌面成像领域的一项新兴技术,在评估MRONJ方面具有诸多优势。本综述旨在总结通过CBCT观察到的MRONJ的放射学特征,并强调其在评估MRONJ方面相对于二维平片的优势。CBCT有能力检测早期MRONJ病变,描述病变的范围和性质,将MRONJ与其他骨病变区分开来,并协助制定治疗计划。通过利用CBCT的优势,临床医生可以增强对MRONJ的理解,改善决策,最终优化患者护理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8ed/11353876/15d11af3f299/diagnostics-14-01700-g001.jpg

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