Buchanan David, Kee Romina, Sadowski Laura S, Garcia Diana
John Stroger Hospital of Cook County (formerly Cook County Hospital), Chicago, IL, and Rush University, Chicago, USA.
Am J Public Health. 2009 Nov;99 Suppl 3(Suppl 3):S675-80. doi: 10.2105/AJPH.2008.137810. Epub 2009 Apr 16.
We assessed the health impact of a housing and case management program, the Chicago Housing for Health Partnership, for homeless people with HIV.
HIV-positive homeless inpatients at a public hospital (n = 105) were randomized to usual care or permanent housing with intensive case management. The primary outcome was survival with intact immunity, defined as CD4 count > or = 200 and viral load < 100,000. Secondary outcomes were viral loads, undetectable viral loads, and CD4 counts.
Outcomes were available for 94 of 105 enrollees (90%). Of 54 intervention participants, 35 (65%) reached permanent housing in program housing agencies. After 1 year, 55% of the intervention and 34% of the usual care groups were alive and had intact immunity (P = .04). Seventeen intervention (36%) and 9 usual care (19%) participants had undetectable viral loads (P = .051). Median viral loads were 0.89 log lower in the intervention group (P = .03). There were no statistical differences in CD4 counts.
Homelessness is a strong predictor of poor health outcomes and complicates the medical management of HIV. This housing intervention improved the health of HIV-positive homeless people.
我们评估了一项住房与病例管理项目——芝加哥健康住房伙伴关系,对感染艾滋病毒的无家可归者的健康影响。
一家公立医院的105名艾滋病毒呈阳性的无家可归住院患者被随机分为接受常规护理或获得永久性住房并接受强化病例管理。主要结局是免疫功能完好的生存情况,定义为CD4细胞计数≥200且病毒载量<100,000。次要结局是病毒载量、病毒载量检测不到以及CD4细胞计数。
105名登记者中有94人(90%)有结局数据。在54名干预参与者中,35人(65%)在项目住房机构中获得了永久性住房。1年后,干预组55%的人和常规护理组34%的人存活且免疫功能完好(P = 0.04)。17名干预参与者(36%)和9名常规护理参与者(19%)的病毒载量检测不到(P = 0.051)。干预组的病毒载量中位数低0.89个对数(P = 0.03)。CD4细胞计数无统计学差异。
无家可归是健康结局不佳的一个有力预测因素,并且使艾滋病毒的医疗管理复杂化。这项住房干预改善了艾滋病毒呈阳性的无家可归者的健康状况。