与英夫利昔单抗治疗而无甲氨蝶呤治疗相关的间质性肺炎。
Interstitial pneumonitis associated with infliximab therapy without methotrexate treatment.
机构信息
First Department of Internal Medicine, University of Toyama, 2630 Sugitani, Toyama, 930-0194, Japan.
出版信息
Rheumatol Int. 2009 Dec;30(2):275-6. doi: 10.1007/s00296-009-0931-6.
Tumor necrosis factor (TNF)-α inhibitors are increasingly being used to treat rheumatoid arthritis. Infliximab (INF) is a TNF-α inhibitor that is usually used in combination with methotrexate (MTX). Interstitial lung disease (ILD) during combination therapy has been attributed to MTX rather than INF. However, INF-associated ILD without combination with MTX has recently been reported. We describe herein a case of severe ILD secondary to INF without MTX therapy.
肿瘤坏死因子 (TNF)-α 抑制剂越来越多地被用于治疗类风湿关节炎。英夫利昔单抗 (INF) 是一种 TNF-α 抑制剂，通常与甲氨蝶呤 (MTX) 联合使用。联合治疗期间的间质性肺疾病 (ILD) 归因于 MTX 而不是 INF。然而，最近有报道称存在不与 MTX 联合使用的 INF 相关 ILD。我们在此描述了一例继发于无 MTX 治疗的 INF 的严重 ILD 病例。
Zotero 插件