使用前列腺素逆转原发性肝移植无功能状态。
Reversal of primary liver graft non-function using prostaglandins.
作者信息
Grazi G L, Mazziotti A, Sama C, Stefanini G F, Gozzetti G
机构信息
2nd Department of Surgery, University of Bologna, Ospedale S. Orsola, Italy.
出版信息
Hepatogastroenterology. 1991 Jun;38(3):254-6.
Primary graft non-function remains one of the most life-threatening problems after liver transplantation. Its etiology is still unclear. Liver retransplantation is the only therapeutic alternative to this problem. The PGE1 series of prostaglandins have recently been successfully used in the treatment of transplanted organ dysfunction. In this paper we describe a case of primary graft non-function successfully treated with continuous infusion of prostaglandin PGE1, and we briefly discuss the pathogenetic and therapeutic hypotheses.
原发性移植肝无功能仍然是肝移植后最危及生命的问题之一。其病因仍不清楚。再次肝移植是解决这一问题的唯一治疗选择。前列腺素E1系列最近已成功用于治疗移植器官功能障碍。本文描述了一例通过持续输注前列腺素E1成功治疗原发性移植肝无功能的病例，并简要讨论了其发病机制和治疗假说。
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