Department of Otolaryngology, Warrington Hospital, Lovely Lane, Warrington WA5 1QG, United Kingdom.
Head Neck. 2010 Mar;32(3):411-4. doi: 10.1002/hed.21095.
Merkel Cell Carcinoma (MCC) is a rare neurendocrine tumor of cutaneous origin.
A 79-year-old woman was seen with a neck lump and a lesion in the left nasal vestibule. Biopsy of the lesion revealed a primary neurendocrine MCC of the skin of the nasal vestibule with metastases to the cervical lymph nodes. The patient decided against any further active treatment. Follow-up of patient for 30 months showed spontaneous regression of the lesions without any active treatment.
Although spontaneous resolution of MCC has been described for other head neck sites, there has not been any published case of nasal MCC regression. We present this rare case of nasal MCC with neck metastases and its regression.
Merkel 细胞癌（MCC）是一种罕见的皮肤起源的神经内分泌肿瘤。
一名 79 岁女性因颈部肿块和左侧鼻腔前庭病变就诊。病变活检显示原发性神经内分泌 MCC 发生于鼻腔前庭皮肤，伴有颈部淋巴结转移。患者决定不进行任何进一步的积极治疗。对患者进行 30 个月的随访显示，病变未经任何积极治疗而自发消退。
虽然已有其他头颈部部位 MCC 自发消退的描述，但尚未有任何关于鼻腔 MCC 消退的报道。我们报告了这例罕见的鼻腔 MCC 伴颈部转移及其消退。
