Holden Arthur, Park June-Soo, Chu Vivian, Kim Michele, Choi Grace, Shi Yating, Chin Tiffany, Chun Christina, Linthicum Janet, Walton Brian J, Hooper Kim
Department of Toxic Substances Control, California Environmental Protection Agency, Berkeley, California 94710, USA.
Environ Toxicol Chem. 2009 Sep;28(9):1906-11. doi: 10.1897/08-594.1.
High (maximum of 4.1 ppm lipid weight) levels of BDE-209 and other higher brominated diphenyl ethers (BDEs) found in California, USA, peregrine falcon (Falco peregrinus) eggs (n = 95) provided an opportunity to examine homolog profiles of nona-, octa-, and hepta-BDEs as possible evidence for biological debromination of BDE-209. We found two congeners in eggs, an unidentified hepta-BDE (BDE-heptaUNK) and BDE-202 (octa-BDE) that are not present in commercial mixtures. In addition, BDE-208 (nona-BDE) was present at much higher (10-fold) proportions in eggs than in commercial mixtures. To examine whether these unusual homolog patterns arose from assimilation of environmentally degraded BDE commercial mixtures, we compared nona-hepta-BDE homolog profiles of peregrine falcon eggs with those of weathered BDEs present in various abiotic matrices (sludge, sediment, and dusts). We found the profiles differed significantly: BDE-207 was the major nona-BDE in eggs, whereas BDE-206 was the major nona-BDE in abiotic matrices. Thus, the evidence for the biological debromination of BDE-209 in peregrine falcons is twofold: Eggs have two congeners (BDE-202 and -heptaUNK) that are not reported for any commercial mixtures nor in the abiotic matrices examined thus far, and eggs have higher-brominated BDE homolog patterns that are different from those found in commercial mixtures or environmental matrices.
在美国加利福尼亚州游隼（Falco peregrinus）的蛋（n = 95）中发现了高含量（最高达4.1 ppm脂质重量）的BDE - 209和其他高溴化二苯醚（BDEs），这为研究九溴、八溴和七溴二苯醚的同系物谱提供了契机，作为BDE - 209生物脱溴的可能证据。我们在蛋中发现了两种同系物，一种未鉴定的七溴二苯醚（BDE - heptaUNK）和BDE - 202（八溴二苯醚），它们不存在于商业混合物中。此外，BDE - 208（九溴二苯醚）在蛋中的比例比在商业混合物中高得多（10倍）。为了研究这些不寻常的同系物模式是否源于对环境降解的BDE商业混合物的同化，我们将游隼蛋的九溴 - 七溴二苯醚同系物谱与各种非生物基质（污泥、沉积物和灰尘）中存在的风化BDEs的同系物谱进行了比较。我们发现这些谱有显著差异：BDE - 207是蛋中主要的九溴二苯醚，而BDE - 206是非生物基质中主要的九溴二苯醚。因此，游隼中BDE - 209生物脱溴的证据有两方面：蛋中有两种同系物（BDE - 202和 - heptaUNK），在任何商业混合物中以及迄今为止检测的非生物基质中均未报告过，并且蛋中具有与商业混合物或环境基质中不同的高溴化BDE同系物模式。
