蒙古人种群体中补体成分I的多态性：一种新的基因变体IF A2。

Polymorphism of complement component I in Mongoloid populations: a new genetic variant IF A2.

作者信息

Ding M, Umetsu K, Yuasa I, Nakamura S, Choi W Y, Suzuki T

机构信息

Department of Forensic Serology, Faculty of Forensic Medicine, China Medical University, Shenyang.

出版信息

Hum Hered. 1991;41(3):206-8. doi: 10.1159/000154002.

DOI:10.1159/000154002

PMID:1937494

Abstract

The genetic polymorphism of the complement component I (IF) was investigated in 282 Chinese, 239 Koreans and 198 Japanese. The 3 common IF phenotypes (A, AB and B) and a new rare IF phenotype (BA2) were observed. The obtained allele frequencies are as follows: IFA = 0.0993 and IFB = 0.9007 in Chinese; IFA = 0.0921 and IFB = 0.9079 in Koreans; IFA = 0.0985, IFB = 0.8990 and IF*A2 = 0.0025 in Japanese. These 3 Mongoloid populations showed a much higher degree of IF polymorphism than Caucasian populations.

摘要

在282名中国人、239名韩国人和198名日本人中研究了补体成分I（IF）的基因多态性。观察到3种常见的IF表型（A、AB和B）以及一种新的罕见IF表型（BA2）。获得的等位基因频率如下：中国人中IFA = 0.0993，IFB = 0.9007；韩国人中IFA = 0.0921，IFB = 0.9079；日本人中IFA = 0.0985，IFB = 0.8990，IF*A2 = 0.0025。这3个蒙古人种群体显示出比高加索人群更高程度的IF多态性。