Jon Duk-In, Hong Narei, Yoon Bo-Hyun, Jung Han Yong, Ha Kyooseob, Shin Young Chul, Bahk Won-Myong
Department of Psychiatry, Hallym University, Anyang 431-070, South Korea.
Compr Psychiatry. 2009 May-Jun;50(3):286-91. doi: 10.1016/j.comppsych.2008.07.008. Epub 2008 Sep 20.
This study aimed to elucidate the validity and reliability of the Korean version of the Mood Disorder Questionnaire (K-MDQ), which is a screening instrument developed for bipolar disorders.
This study translated the MDQ into Korean to produce the K-MDQ. The K-MDQ was applied to 126 outpatients with bipolar disorder clinically diagnosed by Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition and 112 controls without a psychiatric history. The long-term test-retest reliability with a 10-month interval was investigated in 30 bipolar outpatients.
The internal consistency (Cronbach alpha) of the K-MDQ was .88. The correlations between each item and the total score ranged from 0.43 to 0.76 and were all statistically significant (P < .001). Factor analysis revealed 3 factors that explained 59.5% of the total variance. The mean total score was higher in patients (8.48) than in controls (4.51) (P < .001). A total K-MDQ score of at least 7 was chosen as the optimal cutoff, with the 2 parts of the questionnaire on symptoms clustering and functional problems being excluded, since this provided good sensitivity (0.75) and specificity (0.69). The Pearson correlation coefficient for the total test-retest score was 0.63 (P < .001), and the intraclass correlation coefficient was 0.77 (P < .001; 95% confidence interval, 0.52-0.89).
These findings demonstrated the adequate validity and reliability of the K-MDQ, suggesting that this instrument is useful for screening bipolar disorders in Korea. However, we recommend that the original criteria be modified to improve the sensitivity.
本研究旨在阐明韩国版心境障碍问卷(K-MDQ)的有效性和可靠性,该问卷是一种为双相情感障碍开发的筛查工具。
本研究将心境障碍问卷(MDQ)翻译成韩语以生成K-MDQ。K-MDQ应用于126例根据《精神疾病诊断与统计手册》第四版临床诊断为双相情感障碍的门诊患者以及112例无精神病史的对照者。对30例双相情感障碍门诊患者进行了间隔10个月的长期重测信度研究。
K-MDQ的内部一致性(克朗巴哈α系数)为0.88。各项目与总分的相关性在0.43至0.76之间,均具有统计学意义(P <.001)。因子分析揭示了3个因子,解释了总方差的59.5%。患者的平均总分(8.48)高于对照者(4.51)(P <.001)。选择K-MDQ总分至少为7作为最佳截断值,排除问卷中关于症状聚类和功能问题的两部分内容,因为这样可提供良好的敏感性(0.75)和特异性(0.69)。重测总分的皮尔逊相关系数为0.63(P <.001),组内相关系数为0.77(P <.001;95%置信区间,0.52 - 0.89)。
这些结果表明K-MDQ具有足够的有效性和可靠性,提示该工具在韩国可用于双相情感障碍的筛查。然而,我们建议修改原始标准以提高敏感性。