Cheung Bernard M Y, Ong Kwok Leung, Cherny Stacey S, Sham Pak-Chung, Tso Annette W K, Lam Karen S L
Department of Clinical Pharmacology, School of Clinical and Experimental Medicine, University of Birmingham, United Kingdom.
Am J Med. 2009 May;122(5):443-53. doi: 10.1016/j.amjmed.2008.09.047.
Changes in the prevalence, treatment, and management of diabetes in the United States from 1999 to 2006 were studied using data from the National Health and Nutrition Examination Survey.
Data on 17,306 participants aged 20 years or more were analyzed. Glycemic, blood pressure, and cholesterol targets were glycosylated hemoglobin less than 7.0%, blood pressure less than 130/80 mm Hg, and low-density lipoprotein (LDL) cholesterol less than 100 mg/dL, respectively.
The prevalence of diagnosed diabetes was 6.5% from 1999 to 2002 and 7.8% from 2003 to 2006 (P < .05) and increased significantly in women, non-Hispanic whites, and obese people. Although there were no significant changes in the pattern of antidiabetic treatment, the age-adjusted percentage of people with diagnosed diabetes achieving glycemic and LDL targets increased from 43.1% to 57.1% (P < .05) and from 36.1% to 46.5% (P < .05), respectively. Glycosylated hemoglobin decreased from 7.62% to 7.15% during this period (P < .05). The age-adjusted percentage achieving all 3 targets increased insignificantly from 7.0% to 12.2%.
The prevalence of diagnosed diabetes increased significantly from 1999 to 2006. The proportion of people with diagnosed diabetes achieving glycemic and LDL targets also increased. However, there is a need to achieve glycemic, blood pressure, and LDL targets simultaneously.
利用美国国家健康与营养检查调查的数据,研究1999年至2006年美国糖尿病患病率、治疗及管理情况的变化。
对17306名20岁及以上参与者的数据进行分析。血糖、血压和胆固醇目标分别为糖化血红蛋白低于7.0%、血压低于130/80 mmHg以及低密度脂蛋白(LDL)胆固醇低于100 mg/dL。
1999年至2002年确诊糖尿病的患病率为6.5%,2003年至2006年为7.8%(P < 0.05),且在女性、非西班牙裔白人及肥胖人群中显著增加。尽管抗糖尿病治疗模式无显著变化,但确诊糖尿病患者达到血糖和LDL目标的年龄调整百分比分别从43.1%增至57.1%(P < 0.05)和从36.1%增至46.5%(P < 0.05)。在此期间,糖化血红蛋白从7.62%降至7.15%(P < 0.05)。达到所有3项指标的年龄调整百分比从7.0%增至12.2%,增幅不显著。
1999年至2006年,确诊糖尿病的患病率显著增加。确诊糖尿病患者达到血糖和LDL目标的比例也有所增加。然而,仍需同时实现血糖、血压和LDL目标。