Ong Kwok Leung, Cheung Bernard M Y, Wong Louisa Y F, Wat Nelson M S, Tan Kathryn C B, Lam Karen S L
Department of Medicine and the Research Centre of Heart, Brain, Hormone and Healthy Ageing, Faculty of Medicine, University of Hong Kong.
Ann Epidemiol. 2008 Mar;18(3):222-9. doi: 10.1016/j.annepidem.2007.10.007. Epub 2008 Jan 16.
This study aimed to examine the trends in prevalence, treatment, and control of diagnosed diabetes in United States adults 20 years of age or older.
Data from the National Health and Nutrition Examination Survey 1999-2004 were used. Glycemic, blood pressure, and total cholesterol target levels were defined as having glycosylated hemoglobin <7.0%, blood pressure <130/80 mm Hg, and total cholesterol <200 mg/dL, respectively.
The prevalence of diagnosed diabetes was 7.8% in 2003-2004 and increased significantly in people aged 40-59 years, women, non-Hispanic whites, and obese people in the period 1999-2004. Although there was no significant change in the pattern of antidiabetic treatment, the age-adjusted percentage of people with diagnosed diabetes achieving glycemic and blood pressure target levels increased from 35.8% to 57.1% (p = 0.002) and from 35.7% to 48.3% (p = 0.04), respectively. However, there were only insignificant increases in percentages of those persons achieving total cholesterol target level (from 48.8% to 50.4%) and those achieving all 3 target levels (from 7.5% to 13.2%).
In 1999-2004, the prevalence of diagnosed diabetes increased significantly in some subgroups of the population. However, the increases in percentages of people with diabetes achieving glycemic and blood pressure targets are encouraging, although there is room for improvement.
本研究旨在调查美国20岁及以上成年人中已确诊糖尿病的患病率、治疗情况及控制情况的趋势。
使用了1999 - 2004年美国国家健康与营养检查调查的数据。血糖、血压和总胆固醇的目标水平分别定义为糖化血红蛋白<7.0%、血压<130/80 mmHg和总胆固醇<200 mg/dL。
2003 - 2004年已确诊糖尿病的患病率为7.8%,在1999 - 2004年期间,40 - 59岁人群、女性、非西班牙裔白人及肥胖人群中的患病率显著上升。尽管抗糖尿病治疗模式没有显著变化,但已确诊糖尿病且达到血糖和血压目标水平的人群经年龄调整后的百分比分别从35.8%增至57.1%(p = 0.002)和从35.7%增至48.3%(p = 0.04)。然而,达到总胆固醇目标水平的人群百分比(从48.8%增至50.4%)和达到所有三个目标水平的人群百分比(从7.5%增至13.2%)仅有不显著的增加。
在1999 - 2004年期间,已确诊糖尿病的患病率在部分人群亚组中显著上升。不过,糖尿病患者达到血糖和血压目标的百分比有所增加,这令人鼓舞,尽管仍有改进空间。