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Interaction of synthetic 10-tyrosyl analogues of secretin with hormone receptors on pancreatic acinar cells.

作者信息

Gardner J D, Conlon T P, Beyerman H C, Van Zon A

出版信息

Gastroenterology. 1977 Jul;73(1):52-6.

PMID:193759
Abstract
摘要

相似文献

1
Interaction of synthetic 10-tyrosyl analogues of secretin with hormone receptors on pancreatic acinar cells.促胰液素的合成10-酪氨酰类似物与胰腺腺泡细胞上激素受体的相互作用。
Gastroenterology. 1977 Jul;73(1):52-6.
2
Interaction of secretin5-27 and its analogues with hormone receptors on pancreatic acini.促胰液素5 - 27及其类似物与胰腺腺泡上激素受体的相互作用。
Biochim Biophys Acta. 1979 Apr 3;583(4):491-503. doi: 10.1016/0304-4165(79)90066-7.
3
Interaction of peptides related to secretin with hormone receptors on pancreatic acinar cells.
Gastroenterology. 1976 Dec;71(6):965-70.
4
Effects of alcohols on the actions of VIP and secretin on acinar cells from guinea pig pancreas.酒精对血管活性肠肽（VIP）和促胰液素作用于豚鼠胰腺腺泡细胞的影响。
Gastroenterology. 1979 May;76(5 Pt 1):917-25.
5
Importance of the amino acid in position 15 of VIP and secretin in influencing their interactions with membrane receptors on pancreatic acinar cells.血管活性肠肽（VIP）和促胰液素中第15位氨基酸在影响它们与胰腺腺泡细胞膜受体相互作用方面的重要性。
Endocrinol Jpn. 1980 Dec;27 Suppl 1:1-5. doi: 10.1507/endocrj1954.27.supplement_1.
6
Identification and characterization of receptors for secretagogues on pancreatic acinar cells.胰腺腺泡细胞上促分泌素受体的鉴定与特性分析。
Fed Proc. 1981 Aug;40(10):2486-96.
7
Action of VIP and secretin on adenylate cyclase activity in acinar cells from guinea pig pancreas.血管活性肠肽和促胰液素对豚鼠胰腺腺泡细胞中腺苷酸环化酶活性的作用。
Gastroenterology. 1979 Oct;77(4 Pt 1):704-13.
8
[Hormone and neuroeffector receptors in gastroenterology. A concrete example: the VIP (vasoactive intestinal peptide) receptors].
Acta Gastroenterol Belg. 1982 Jul-Aug;45(7-8):280-91.
9
Characterization of receptors for gastrointestinal peptides.胃肠肽受体的特性分析
Scand J Gastroenterol Suppl. 1983;82:7-18.
10
Pancreatic secretion and cyclic AMP in pancreatic tissue after intravenous infusion of secretin and vasoactive intestinal peptide in cats.静脉注射促胰液素和血管活性肠肽后猫胰腺组织中的胰腺分泌与环磷酸腺苷
Acta Physiol Pol. 1980 Jan-Feb;31(1):53-9.

引用本文的文献

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Structure and dynamics of the active Gs-coupled human secretin receptor.活性 Gs 偶联人分泌素受体的结构与动力学。
Nat Commun. 2020 Aug 18;11(1):4137. doi: 10.1038/s41467-020-17791-4.
2
Rational development of a high-affinity secretin receptor antagonist.高亲和力促胰液素受体拮抗剂的合理开发。
Biochem Pharmacol. 2020 Jul;177:113929. doi: 10.1016/j.bcp.2020.113929. Epub 2020 Mar 23.
3
Use of Cysteine Trapping to Map Spatial Approximations between Residues Contributing to the Helix N-capping Motif of Secretin and Distinct Residues within Each of the Extracellular Loops of Its Receptor.
利用半胱氨酸捕获技术绘制促胰液素螺旋N端封帽基序中残基与受体每个细胞外环内不同残基之间的空间近似关系。
J Biol Chem. 2016 Mar 4;291(10):5172-84. doi: 10.1074/jbc.M115.706010. Epub 2016 Jan 6.
4
Insights into the impact of phenolic residue incorporation at each position along secretin for receptor binding and biological activity.关于在促胰液素的每个位置掺入酚类残基对受体结合和生物活性影响的见解。
Regul Pept. 2013 Jan 10;180:5-11. doi: 10.1016/j.regpep.2012.10.001. Epub 2012 Nov 8.
5
Mapping spatial approximations between the amino terminus of secretin and each of the extracellular loops of its receptor using cysteine trapping.利用半胱氨酸捕获技术绘制分泌素氨基末端与受体各胞外环之间的空间近似图。
FASEB J. 2012 Dec;26(12):5092-105. doi: 10.1096/fj.12-212399. Epub 2012 Sep 10.
6
Lactam constraints provide insights into the receptor-bound conformation of secretin and stabilize a receptor antagonist.内酰胺限制提供了关于分泌素受体结合构象的见解，并稳定了受体拮抗剂。
Biochemistry. 2011 Sep 27;50(38):8181-92. doi: 10.1021/bi2008036. Epub 2011 Aug 30.
7
Molecular basis of secretin docking to its intact receptor using multiple photolabile probes distributed throughout the pharmacophore.使用分布在整个药效基团中的多个光不稳定探针，阐明分泌素与其完整受体对接的分子基础。
J Biol Chem. 2011 Jul 8;286(27):23888-99. doi: 10.1074/jbc.M111.245969. Epub 2011 May 12.
8
Elucidation of the active conformation of the amino terminus of receptor-bound secretin using intramolecular disulfide bond constraints.利用分子内二硫键约束阐明受体结合促胰液素氨基末端的活性构象。
Bioorg Med Chem Lett. 2010 Oct 15;20(20):6040-4. doi: 10.1016/j.bmcl.2010.08.062. Epub 2010 Aug 15.
9
Secretin occupies a single protomer of the homodimeric secretin receptor complex: insights from photoaffinity labeling studies using dual sites of covalent attachment.缩胆囊素占据同二聚体缩胆囊素受体复合物的单个单体：来自使用共价连接的双重位点的光亲和标记研究的见解。
J Biol Chem. 2010 Mar 26;285(13):9919-9931. doi: 10.1074/jbc.M109.089730. Epub 2010 Jan 25.
10
Spatial approximation between secretin residue five and the third extracellular loop of its receptor provides new insight into the molecular basis of natural agonist binding.促胰液素残基5与其受体的第三个细胞外环之间的空间近似性为天然激动剂结合的分子基础提供了新的见解。
Mol Pharmacol. 2008 Aug;74(2):413-22. doi: 10.1124/mol.108.047209. Epub 2008 May 8.