静脉注射促胰液素和血管活性肠肽后猫胰腺组织中的胰腺分泌与环磷酸腺苷
Pancreatic secretion and cyclic AMP in pancreatic tissue after intravenous infusion of secretin and vasoactive intestinal peptide in cats.
作者信息
Mikoś E, Mitis-Musioł M, Radecki T, Konturek S
出版信息
Acta Physiol Pol. 1980 Jan-Feb;31(1):53-9.
PMID:6246717
Abstract
This study demonstrates that secretin and vasoactive intestinal peptide increased dose-dependently pancreatic bicarbonate secretion and cyclic AMP content in pancreatic tissue homogenates in cats. It is concluded that both hormones may act on the same receptor site in the pancreas and that their action is based on stimulation of the adenylate cyclase-cyclic AMP system.
摘要
本研究表明，在猫的胰腺组织匀浆中，促胰液素和血管活性肠肽可使胰腺碳酸氢盐分泌和环磷酸腺苷（cAMP）含量呈剂量依赖性增加。得出的结论是，这两种激素可能作用于胰腺中的同一受体位点，且它们的作用基于对腺苷酸环化酶 - 环磷酸腺苷系统的刺激。
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