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在猪模型中使用射频消融进行电视辅助肺切除术。

Video-assisted lung resection using radiofrequency ablation in a porcine model.

作者信息

Tomos Periklis, Felekouras Evangelos, Poupalou Anna, Kontos Michael, Pappa Penny, Kavatzas Nikolaos, Pavlopoulos Dionisios, Kostakis Alkiviadis, Papalois Apostolos, Tsigris Christos

机构信息

2nd Propaedeutic Department of Surgery, University of Athens, Laiko Hospital, Athens, Greece.

出版信息

J Surg Res. 2009 Jun 15;154(2):279-83. doi: 10.1016/j.jss.2008.06.011. Epub 2008 Jul 11.

DOI:10.1016/j.jss.2008.06.011
PMID:19376530
Abstract

BACKGROUND

The aim of this study was to assess the feasibility, efficacy, and safety of video-assisted lingula resection using radiofrequency ablation (RFA) with internally cooled electrodes in a porcine model.

MATERIALS AND METHODS

Six domestic pigs underwent RFA-assisted thoracoscopic lingulectomy. RFA was the only aerostatic and hemostatic method applied throughout the operation. After 30 d, the animals were sacrificed for the study of the macroscopic and microscopic effects of the technique.

RESULTS

No signs of pneumothorax, blood loss, or infection were observed up to 1 mo postoperatively. There was no mortality either during or after surgery. The histopathology of the lung revealed three clearly demarcated zone lesions.

CONCLUSIONS

Our study demonstrates that thoracoscopic lingulectomy using RFA energy is technically feasible. RFA energy is an effective and safe aerostatic and hemostatic method in the porcine model.

摘要

背景

本研究旨在评估在猪模型中使用带内部冷却电极的射频消融(RFA)进行电视辅助舌叶切除术的可行性、有效性和安全性。

材料与方法

六只家猪接受了RFA辅助的胸腔镜舌叶切除术。RFA是整个手术中唯一应用的气体静态和止血方法。30天后,处死动物以研究该技术的宏观和微观效果。

结果

术后1个月内未观察到气胸、失血或感染迹象。手术期间或术后均无死亡。肺组织病理学显示有三个界限清晰的区域病变。

结论

我们的研究表明,使用RFA能量进行胸腔镜舌叶切除术在技术上是可行的。在猪模型中,RFA能量是一种有效且安全的气体静态和止血方法。

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