Kreiner A J, Thatar Vento V, Levinas P, Bergueiro J, Di Paolo H, Burlon A A, Kesque J M, Valda A A, Debray M E, Somacal H R, Minsky D M, Estrada L, Hazarabedian A, Johann F, Suarez Sandin J C, Castell W, Davidson J, Davidson M, Giboudot Y, Repetto M, Obligado M, Nery J P, Huck H, Igarzabal M, Fernandez Salares A
Departamento de Física, Comisión Nacional de Energía Atómica, Av. Gral Paz 1499 (1650), San Martín, Buenos Aires, Argentina.
Appl Radiat Isot. 2009 Jul;67(7-8 Suppl):S266-9. doi: 10.1016/j.apradiso.2009.03.084. Epub 2009 Mar 27.
In this work we describe the present status of an ongoing project to develop a tandem-electrostatic-quadrupole (TESQ) accelerator facility for accelerator-based (AB) BNCT at the Atomic Energy Commission of Argentina in Buenos Aires. The project final goal is a machine capable of delivering 30 mA of 2.4 MeV protons to be used in conjunction with a neutron production target based on the (7)Li(p,n)(7)Be reaction slightly beyond its resonance at 2.25 MeV. These are the specifications needed to produce sufficiently intense and clean epithermal neutron beams, based on the (7)Li(p,n)(7)Be reaction, to perform BNCT treatment for deep-seated tumors in less than an hour. An electrostatic machine is the technologically simplest and cheapest solution for optimized AB-BNCT. The machine being designed and constructed is a folded TESQ with a high-voltage terminal at 1.2 MV intended to work in air. Such a machine is conceptually shown to be capable of transporting and accelerating a 30 mA proton beam to 2.4 MeV. The general geometric layout, its associated electrostatic fields, and the acceleration tube are simulated using a 3D finite element procedure. The design and construction of the ESQ modules is discussed and their electrostatic fields are investigated. Beam transport calculations through the accelerator are briefly mentioned. Likewise, work related to neutron production targets, strippers, beam shaping assembly and patient treatment room is briefly described.
在这项工作中,我们描述了一个正在进行的项目的现状,该项目旨在为位于布宜诺斯艾利斯的阿根廷原子能委员会开发一种用于基于加速器的硼中子俘获疗法(AB-BNCT)的串联静电四极(TESQ)加速器设施。该项目的最终目标是制造一台能够提供30 mA的2.4 MeV质子的机器,该质子将与基于(7)Li(p,n)(7)Be反应的中子产生靶配合使用,该反应略高于其在2.25 MeV处的共振。这些是基于(7)Li(p,n)(7)Be反应产生足够强度和纯净的超热中子束,以便在不到一小时的时间内对深部肿瘤进行BNCT治疗所需的规格。静电机器是优化AB-BNCT技术上最简单且最便宜的解决方案。正在设计和建造的机器是一种折叠式TESQ,其高压终端为1.2 MV,旨在在空气中工作。从概念上讲,这样的机器能够将30 mA的质子束传输并加速到2.4 MeV。使用3D有限元程序模拟了总体几何布局、其相关的静电场和加速管。讨论了ESQ模块的设计和构造,并研究了它们的静电场。简要提及了通过加速器的束流传输计算。同样,简要描述了与中子产生靶、剥离器、束流整形组件和患者治疗室相关的工作。