Watt Andrew J, Chung Kevin C
Department of Surgery, Stanford University Hospitals and Clinics, Palo Alto, CA 94304, USA.
Hand Clin. 2009 May;25(2):215-27. doi: 10.1016/j.hcl.2009.01.001.
Congenital limb duplications include pre- and post-axial polydactyly, central polydactyly, and the mirror-hand spectrum. Treatment of these duplications constitutes a significant functional and aesthetic challenge for the reconstructive hand surgeon. This article provides an inclusive review of the embryologic and molecular mechanisms underlying these deformities and focuses on their clinical treatment. The anatomic variation, classification, surgical treatment, and outcomes of surgical intervention are reviewed for each of the disorders of duplication.
先天性肢体重复畸形包括轴前和轴后多指畸形、中央多指畸形以及镜手谱系。对于重建手外科医生而言,治疗这些重复畸形在功能和美观方面都是重大挑战。本文全面综述了这些畸形背后的胚胎学和分子机制,并着重探讨其临床治疗方法。针对每种重复畸形疾病,本文回顾了其解剖变异、分类、手术治疗及手术干预的结果。