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近端胃迷走神经切断术。标准技术与联合大弯侧去神经支配的扩展技术之间的比较研究。

Proximal gastric vagotomy. A comparative study between the standard technique and the extended technique associated with denervation of the greater curvature.

作者信息

D'Albuquerque L A, Gama-Rodrigues J, De Miranda M F, Genzini T, Sakai P, Laudanna A A, Pinotti H W

机构信息

Department of Gastroenterology, Hospital das Clínicas, University of Saõ Paulo, College of Medicine, Brazil.

出版信息

Int Surg. 1991 Jul-Sep;76(3):137-41.

PMID:1938199
Abstract

Forty-six patients in the postoperative period of proximal gastric vagotomy (PGV) for duodenal ulcer (DU) were studied comparatively to verify whether the dividing of the gastroepiploic nerves (Rosati's maneuver) can reduce or not the occurrence of recurrent ulcer as it was proposed. Twenty-one patients who underwent PGV associated with Rosati's maneuver (PGV-R) were compared to 25 after standard PGV (PGV-S), according to several criteria: (1) clinical evaluation; (2) pre and postoperative basal and pentagastrin-stimulated gastric acidity; (3) postoperative basal and pentagastrin-stimulated serum pepsinogen; (4) postoperative basal and sham feeding-stimulated serum gastrin; (5) postoperative endoscopy; (6) endoscopic Congo red test. Both groups were similar (P greater than 0.05) as to age, sex, levels of preoperative gastric acidity and had a 24.4 month average follow-up (12 to 58 months). There has been no significant difference between the techniques studied as to clinical, secretory, morphological or hormonal gastric tests, although PGV-R proved more effective in reducing basal gastric acidity than PGV-S (P less than 0.05). We concluded that Rosati's maneuver does not improve the results obtained with PGV, although it provided greater reduction of basal gastric acidity than PGV-S.

摘要

对46例因十二指肠溃疡(DU)接受近端胃迷走神经切断术(PGV)术后的患者进行了比较研究,以验证胃网膜神经切断术(罗萨蒂手术)是否能如所提议的那样减少复发性溃疡的发生。根据以下几个标准,将21例行PGV联合罗萨蒂手术(PGV-R)的患者与25例行标准PGV(PGV-S)的患者进行比较:(1)临床评估;(2)术前和术后基础胃酸及五肽胃泌素刺激后的胃酸分泌;(3)术后基础胃酸及五肽胃泌素刺激后的血清胃蛋白酶原;(4)术后基础胃酸及假饲刺激后的血清胃泌素;(5)术后内镜检查;(6)内镜刚果红试验。两组在年龄、性别、术前胃酸水平方面相似(P>0.05),平均随访24.4个月(12至58个月)。在所研究的技术之间,在临床、分泌、形态学或激素方面的胃检查上没有显著差异,尽管PGV-R在降低基础胃酸方面比PGV-S更有效(P<0.05)。我们得出结论,罗萨蒂手术并没有改善PGV所取得的结果,尽管它比PGV-S能更大程度地降低基础胃酸。

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