Farruggia Piero, D'Angelo Paolo, Acquaviva Antonio, Trizzino Antonino, Tucci Fabio, Cilloni Daniela, Messa Francesca, D'Ambrosio Alfonso, Aricò Maurizio
Pediatric Hematology & Oncology, G. Di Cristina Children's Hospital, Palermo, Italy.
Pediatr Hematol Oncol. 2009 Apr-May;26(3):129-35. doi: 10.1080/08880010902773024.
Hypereosinophilic syndrome (HES) represents a heterogeneous group of diseases, some of which are being clarified by recent advances in molecular genetics. It is very rare in children. Uncertainties in classification and lack of prospective studies make therapeutic decisions difficult. The authors report two cases of HES in which steroid therapy was effective.
高嗜酸性粒细胞综合征(HES)是一组异质性疾病,随着分子遗传学的最新进展,其中一些疾病正逐渐明晰。它在儿童中非常罕见。分类的不确定性和前瞻性研究的缺乏使得治疗决策变得困难。作者报告了两例高嗜酸性粒细胞综合征,其中类固醇治疗有效。