Koc Filiz, Guzel A Irfan
Department of Neurology, Cukurova University School of Medicine, Mithat Ozsan Street, Adana 01330, Turkey.
J Dermatol. 2009 May;36(5):306-11. doi: 10.1111/j.1346-8138.2009.00644.x.
Neurofibromatosis and Charcot-Marie-Tooth are genetic disorders of the nervous system affecting the development and growth of nerve cells and demyelination of peripheral neurons, respectively. We report a 22-year-old man who presented clinical manifestations of both neurofibromatosis type 1 (NF1) and Charcot-Marie-Tooth type 1A. The simultaneous occurrence of neurofibromatosis and Charcot-Marie-Tooth disease has rarely been reported. More extensive reports and further investigations of this combination will certainly provide a better understanding of this linkage in the near future.
神经纤维瘤病和夏科-马里-图斯病是神经系统的遗传性疾病，分别影响神经细胞的发育和生长以及周围神经元的脱髓鞘。我们报告了一名22岁男性，他同时出现了1型神经纤维瘤病（NF1）和1A型夏科-马里-图斯病的临床表现。神经纤维瘤病和夏科-马里-图斯病同时发生的情况鲜有报道。对这种组合进行更广泛的报告和进一步研究，肯定会在不久的将来让我们对这种联系有更好的理解。
