Ott I, Weber M, Gattenlöhner S, Schwager K, Hagen R, Baier G
Klinik für Hals-Nasen-Ohren-Heilkunde, Kopf-, Hals- und plastische Gesichtschirurgie, Klinikum Darmstadt, Heidelberger Landstrasse 379, 64297, Darmstadt.
HNO. 2010 Mar;58(3):263-7. doi: 10.1007/s00106-008-1861-4.
Rosai-Dorfman disease belongs to the group of childhood histiocytoses and was initially described as sinus histiocytosis with massive lymphadenopathy. Its rare purely extranodal manifestation is primarily found in the head and neck region. An atypical primary manifestation in an elderly patient with multifocal extranodal disease is described, and this pathological entity is reviewed. Specific difficulties concerning differential diagnostic aspects as well as individually appropriate treatment strategies are discussed.
罗萨伊-多夫曼病属于儿童组织细胞增多症,最初被描述为伴有巨大淋巴结病的窦性组织细胞增多症。其罕见的单纯结外表现主要见于头颈部区域。本文描述了一例老年患者多灶性结外疾病的非典型主要表现,并对这一病理实体进行了综述。讨论了鉴别诊断方面的具体困难以及个体化的合适治疗策略。