Kelly D, King T P
Rowett Research Institute, Bucksburn, Aberdeen, UK.
Histochem J. 1991 Jan;23(1):55-60. doi: 10.1007/BF01886508.
Lectins and carbohydrate-specific monoclonal antibodies were used as cytochemical probes to investigate the possible influence of lactation products on the expression of intestinal membrane and secretory glycoconjugates in suckling piglets. Two different lactational regimes were compared; the first involved normal rearing of piglets for 8 weeks on a single dam and the second involved repeated cross-fostering of littermates onto recently farrowed sows, thereby restricting them to early milk. Five histo-blood group phenotypes were recognized within the piglet population: two immature phenotypes, 'O immature' or 'Oi' and 'A immature' or 'Ai', and three mature forms, 'O', 'A' and '-'. Under the normal suckling regime the transition from immature to mature OA phenotypes was evident at the fifth week post partum. However, in the repeatedly cross-fostered piglets this transition was evident much earlier at 3 weeks post partum. It is suggested that qualitative or quantitative variations in milk composition during the sow's lactation may significantly influence the expression of intestinal histo-blood group antigens in her suckling young.
凝集素和碳水化合物特异性单克隆抗体被用作细胞化学探针，以研究泌乳产物对哺乳仔猪肠膜和分泌性糖缀合物表达的可能影响。比较了两种不同的哺乳方式；第一种是让仔猪在单头母猪哺育下正常饲养8周，第二种是将同窝仔猪反复寄养到刚产仔的母猪那里，从而使它们只能吃到初乳。在仔猪群体中识别出了五种组织血型表型：两种未成熟表型，即“O未成熟型”或“Oi”以及“A未成熟型”或“Ai”，还有三种成熟型，即“O”、“A”和“-”。在正常哺乳方式下，产后第五周时从不成熟到成熟的OA表型转变明显。然而，在反复寄养的仔猪中，这种转变在产后3周时就明显得多。研究表明，母猪泌乳期间乳汁成分的质或量的变化可能会显著影响其哺乳幼崽肠组织血型抗原的表达。
