Bochmann F, Howell J P, Meier C, Becht C, Thiel M A
Department of Ophthalmology, Cantonal Hospital of Lucerne, Lucerne, Switzerland.
Klin Monbl Augenheilkd. 2009 Apr;226(4):280-3. doi: 10.1055/s-0028-1109288. Epub 2009 Apr 21.
The disc damage likelihood scale (DDLS) is a new grading system to estimate the amount of optic disc damage in glaucoma patients. The objective of this study was to assess the interobserver agreement of the DDLS and the cup/disc ratio.
The reproducibility of the DDLS and the cup/disc ratio was measured by two masked observers (one glaucoma specialist and one of two resident physicians in their first 6 months of training) staging 42 eyes of 25 patients with glaucoma or ocular hypertension. Disc size, cup/disc ratio and DDLS were documented and the Cohen's kappa was calculated as a measure for interobserver agreement.
The interobserver agreement for the cup/disc ratio was good (Cohen's kappa 0.803). For the DDLS, the interobserver agreement was even better (Cohen's kappa 0.902).
Unlike the cup/disc ratio, which focuses on the excavation, the DDLS is based directly on the thickness of the neuroretinal rim and takes into account the optic disc size. Therefore, the DDLS estimates the glaucomatous damage of the optic disc more precisely than the currently used method. Although this new grading system is more complicated to use in clinical practice, the interobserver agreement for the DDLS in our study setting was very good.
视盘损伤可能性量表(DDLS)是一种用于评估青光眼患者视盘损伤程度的新分级系统。本研究的目的是评估DDLS与杯盘比的观察者间一致性。
由两名盲法观察者(一名青光眼专家和两名接受培训6个月的住院医师中的一名)对25例青光眼或高眼压症患者的42只眼睛进行分期,以此测量DDLS和杯盘比的可重复性。记录视盘大小、杯盘比和DDLS,并计算科恩kappa系数作为观察者间一致性的指标。
杯盘比的观察者间一致性良好(科恩kappa系数为0.803)。对于DDLS,观察者间一致性更好(科恩kappa系数为0.902)。
与专注于视杯凹陷的杯盘比不同,DDLS直接基于神经视网膜 rim的厚度,并考虑了视盘大小。因此,DDLS比目前使用的方法更精确地估计视盘的青光眼性损伤。尽管这种新的分级系统在临床实践中使用起来更复杂,但在我们的研究环境中,DDLS的观察者间一致性非常好。