Osaki Satoru, Sweitzer Nancy K, Rahko Peter S, Murray Margaret A, Hoffmann Jennifer A, Johnson Maryl R, Edwards Niloo M, Kohmoto Takushi
Department of Surgery, Division of Cardiothoracic Surgery, University of Wisconsin School of Medicine and Public Health, Madison, WI 53792-3236, USA.
Congest Heart Fail. 2009 Mar-Apr;15(2):58-62. doi: 10.1111/j.1751-7133.2008.00028.x.
Predictors of myocardial recovery after ventricular assist device (VAD) implantation are not well defined. The authors report their current VAD weaning protocol. Between 2003 and 2006, 38 patients received VAD implants. The authors performed 5 tests in 4 patients in whom echocardiography findings suggested myocardial recovery after implant. The protocol consists of assessing symptoms, electrocardiographic findings, hemodynamics, and cardiac function at baseline and as VAD support is weaned. As a result, 3 patients passed the weaning protocol and were explanted. There has been no recurrence of heart failure 667, 752, and 1007 days after explant, respectively. One patient failed the protocol after 151 days of support because of low cardiac index during the protocol. This patient was transplanted. This current experience of VAD weaning protocol is a novel tool to identify candidates for successful VAD explantation.
心室辅助装置(VAD)植入后心肌恢复的预测因素尚未明确界定。作者报告了他们目前的VAD撤机方案。2003年至2006年期间,38例患者接受了VAD植入。作者对4例植入后超声心动图结果提示心肌恢复的患者进行了5项测试。该方案包括在基线时以及撤掉VAD支持时评估症状、心电图结果、血流动力学和心脏功能。结果,3例患者通过了撤机方案并进行了装置移除。装置移除后分别在667天、752天和1007天未出现心力衰竭复发。1例患者在接受支持151天后因撤机方案期间心脏指数低而未通过该方案。该患者接受了移植。目前这种VAD撤机方案的经验是识别成功进行VAD移除候选者的一种新工具。