Sangi Sibghatullah, Ahmed Shahida P, Channa Muhammad Aslam, Ashfaq Muhammad, Mastoi Shah Murad
Department of Pharmacology, Fatima Jinnah Dental College, Karachi.
J Ayub Med Coll Abbottabad. 2008 Apr-Jun;20(2):118-24.
Opioid dependence is one of the major social and psychiatric problem of society. Unfortunately there is no non opiate treatment available. For centuries man has used plants for their healing proprieties. These plants play a fundamental part in all treatment modalities, both ancient and modern.
This study was conducted to find non opiate treatment for opiate withdrawal. Total 35 known addicts of opiates were included in the study. This study was based on DSM IV criteria for opioid dependence.
This study demonstrates that non opioid treatment for opioid addiction decreases the withdrawal effects significantly. It further demonstrates that there are no changes in physiological parameters of subjects during treatment (BP, Pulse rate etc.). There is increased appetite but no significant weight gain in the subjects.
Non opioid drug Nigella sativa is effective in long-term treatment of opioid dependence. It not merely cures the opioid dependence but also cures the infections and weakness from which majority of addicts suffer.
阿片类药物依赖是社会主要的社会和精神问题之一。不幸的是,目前没有非阿片类药物治疗方法。几个世纪以来,人类一直利用植物的治疗特性。这些植物在古今所有治疗方式中都发挥着重要作用。
本研究旨在寻找治疗阿片类药物戒断的非阿片类药物治疗方法。该研究共纳入35名已知的阿片类药物成瘾者。本研究基于DSM-IV阿片类药物依赖标准。
本研究表明,非阿片类药物治疗阿片类药物成瘾可显著减轻戒断反应。进一步表明,治疗期间受试者的生理参数(血压、脉搏率等)无变化。受试者食欲增加,但体重无显著增加。
非阿片类药物黑种草籽对阿片类药物依赖的长期治疗有效。它不仅能治愈阿片类药物依赖,还能治愈大多数成瘾者所患的感染和虚弱。