Lecerf Jean-Michel
Nutrition Department, Institut Pasteur de Lille, Lille, France.
Nutr Rev. 2009 May;67(5):273-83. doi: 10.1111/j.1753-4887.2009.00194.x.
Fatty acids have been classified into "good" or "bad" groups according to their degree of unsaturation or whether they are "animal fat" or "vegetable fat". Today, it appears that the effects of fatty acids are complex and vary greatly according to the dose and the nature of the molecule. Monounsaturated fatty acids are still considered as having a "neutral" status, but any benefits may be related to the chemical environment of the source food or the associated overall food pattern. Controversy surrounds omega-6 polyunsaturated fatty acids, because even though they lower LDL cholesterol levels, excessive intakes do not appear to be correlated with cardiovascular benefit. The omega-3 fatty acids are known to exert cardiovascular protective effects. Dairy fat and its cardiovascular impact are being evaluated. This review examines the existing literature on the relationships between the different fatty acids and cardiovascular disease.
脂肪酸已根据其不饱和度或是否为“动物脂肪”或“植物油”被分为“好”或“坏”两类。如今,脂肪酸的作用似乎很复杂,并且会因剂量和分子性质的不同而有很大差异。单不饱和脂肪酸仍被视为具有“中性”地位,但任何益处可能与源食物的化学环境或相关的整体饮食模式有关。围绕ω-6多不饱和脂肪酸存在争议,因为尽管它们能降低低密度脂蛋白胆固醇水平,但过量摄入似乎与心血管益处并无关联。已知ω-3脂肪酸具有心血管保护作用。乳脂肪及其对心血管的影响正在评估中。本综述考察了关于不同脂肪酸与心血管疾病之间关系的现有文献。