WHO/OIE/FAO Collaborating Centre for Reference and Research on Leptospirosis, Communicable Diseases Unit, Queensland Health Forensic and Scientific Service, Archerfield, Queensland 4108, Australia. scott
Trans R Soc Trop Med Hyg. 2009 Sep;103(9):958-60. doi: 10.1016/j.trstmh.2009.03.019. Epub 2009 Apr 21.
Lymphocyte counts in patients with leptospirosis have been shown to be variable. This study retrospectively compared lymphocyte counts from the first blood samples taken following hospital presentation in patients with leptospirosis who were either (i) IgM non-reactive, (ii) IgM reactive and microscopic agglutination test (MAT) non-reactive or (iii) IgM and MAT reactive in an effort to determine whether differences in lymphocyte counts are observed in the acute and immune phase of leptospirosis. Statistical differences in lymphocyte counts were observed between the three groups. In conclusion, this study has shown that the phase of leptospiral infection may affect patient lymphocyte counts.
莱姆病患者的淋巴细胞计数一直存在差异。本研究回顾性比较了莱姆病患者入院后首次血液样本中的淋巴细胞计数,这些患者要么(i)IgM 无反应,要么(ii)IgM 有反应但微量凝集试验(MAT)无反应,要么(iii)IgM 和 MAT 均有反应,以确定在莱姆病的急性和免疫期是否观察到淋巴细胞计数的差异。三组间淋巴细胞计数存在统计学差异。总之,本研究表明,钩端螺旋体感染的阶段可能影响患者的淋巴细胞计数。