Abdull Mohammed M, Sivasubramaniam Selvaraj, Murthy Gudlavalleti V S, Gilbert Clare, Abubakar Tafida, Ezelum Christian, Rabiu Mansur M
Specialist Hospital, Bauchi, Nigeria.
Invest Ophthalmol Vis Sci. 2009 Sep;50(9):4114-20. doi: 10.1167/iovs.09-3507. Epub 2009 Apr 22.
Determine causes of blindness and visual impairment among adults aged >or=40 years.
Multistage, stratified, cluster random sampling with probability proportional to size procedures were used to identify a nationally representative sample of 15,027 persons >or=40 years of age. Distance vision was measured with a reduced logMAR tumbling E-chart. Clinical examination included a basic eye examination of all subjects and a more detailed examination of those who had presenting vision <6/12 in either eye. Cause for vision loss was assigned to all subjects with presenting vision <6/12 in any eye.
Of the 15,122 persons aged >or=40 years who were enumerated, 13,599 (89.9%) were examined. In 84%, blindness was avoidable. Uncorrected refractive errors were responsible for 57.1% of moderate (<6/18-6/60) visual impairment. Cataract (43%) was the commonest cause of blindness (<3/60). Prevalence of cataract-related blindness was 1.8% (95% CI: 1.57-2.05) and glaucoma-related blindness was 0.7% (95% CI: 0.55-0.88). Increasing age was associated with increasing prevalence of all major blinding conditions. Females, illiterate persons, and residents in the North East geopolitical zone had significantly higher odds of cataract-induced blindness and severe visual impairment.
The high proportion of avoidable blindness, with half being attributable to cataract alone and uncorrected refractive errors being responsible for 57% of moderate visual impairment, means that appropriate and accessible refraction and surgical services need to be provided. If priority attention is not given, the number of blind and severely visually impaired adults in Nigeria will increase by >40% over the next decade.
确定40岁及以上成年人失明和视力损害的原因。
采用与规模成比例概率的多阶段、分层、整群随机抽样方法,确定一个具有全国代表性的15027名40岁及以上人群的样本。使用简化对数最小分辨角(logMAR)滚动E字视力表测量远视力。临床检查包括对所有受试者进行基本眼部检查,以及对任何一只眼睛视力低于6/12的受试者进行更详细的检查。对任何一只眼睛视力低于6/12的所有受试者确定视力丧失原因。
在统计的15122名40岁及以上人群中,13599人(89.9%)接受了检查。在84%的病例中,失明是可避免的。未矫正屈光不正导致57.1%的中度(<6/18 - 6/60)视力损害。白内障(43%)是失明(<3/60)的最常见原因。白内障相关失明的患病率为1.8%(95%可信区间:1.57 - 2.05),青光眼相关失明的患病率为0.7%(95%可信区间:0.55 - 0.88)。年龄增长与所有主要致盲疾病的患病率增加相关。女性、文盲以及东北部地缘政治区的居民患白内障导致失明和严重视力损害的几率显著更高。
可避免失明的比例很高,其中一半仅归因于白内障,未矫正屈光不正导致57%的中度视力损害,这意味着需要提供适当且可及的验光和手术服务。如果不给予优先关注,尼日利亚失明和严重视力损害的成年人数量在未来十年将增加超过40%。