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小梁切除术后眼压控制的5年回顾性研究:一项回顾性队列研究。

A 5-year retrospective study of intraocular pressure control after trabeculectomy: a retrospective cohort study.

作者信息

Orezime Atima Mayor, Idakwo Ugbede, Komolafe Oyeronke, Emmanuel Otomi Ogho, Eisuke Shimizu, Shintaro Nakayama, Balogun Emmanuel Oluwadare, Dingwoke Emeka John, Jacob Orugun Ayodele, Melchizedek Munaje Ignatius, Douglas Pam Jah

机构信息

ECWA Eye Hospital, Kano.

Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan.

出版信息

Ann Med Surg (Lond). 2023 Apr 15;85(5):1518-1522. doi: 10.1097/MS9.0000000000000621. eCollection 2023 May.

Abstract

UNLABELLED

Glaucoma is a group of diseases that damage the optic nerve in the eye, resulting in vision loss and, in severe cases, blindness. The prevalence of glaucoma and glaucoma blindness is highest in West Africans.

OBJECTIVE

The study presents a 5-year retrospective analysis of intraocular pressure (IOP) and complications after trabeculectomy.

MATERIALS AND METHODS

Trabeculectomy was performed using 5 mg/ml of 5-fluorouracil. A gentle diathermy was performed to secure hemostasis. Using a blade fragment of the scleral thickness, a 4×3 mm rectangular scleral flap was dissected. The central part of the flap was dissected 1 mm into the clear cornea. Before being tailed down, the patient was given topical 0.05% dexamethasone qid, 1% atropine tid, and 0.3% ciprofloxacin qid for 4-6 weeks. Patients with pain were given pain relievers, and all patients with photophobia were given sun protection. A successful surgical outcome was defined as a postoperative IOP of 20 mmHg or less.

RESULTS

There were 161 patients over the 5-year period under review, with men constituting 70.2% of the total. Out of 275 eyes operated on, 82.9% were bilateral cases, while 17.1% were unilateral. Glaucoma was found in both children and adults aged 11-82 years. However, it was observed to predominate between the ages of 51 and 60, with males having the highest incidence. The average preoperative IOP was 24.37 mmHg, while it was 15.24 mmHg postoperatively. The complication with the highest ranking was shallow anterior chamber (24; 8.73%) due to overfiltration, followed by leaking bleb (8; 2.91%). The most common late complications were cataract (32; 11.64%) and fibrotic bleb (8; 2.91%). Bilateral cataracts developed at an average of 25 months after trabeculectomy. It was seen in patients aged 2-3 with a frequency of 9, whereas 5 years after, 77 patients had improved vision, with a postoperative visual acuity of 6/18-6/6.

CONCLUSION

Postoperatively, the patients had satisfying surgical outcomes as a result of the decrease in preoperative IOP. Although postoperative complications occurred, they had no effect on the surgical outcomes because they were temporary and not optically threatening. In our experience, trabeculectomy is an effective and safe procedure for achieving IOP control.

摘要

未标注

青光眼是一组损害眼部视神经的疾病,可导致视力丧失,严重时可致失明。青光眼及青光眼性失明的患病率在西非人群中最高。

目的

本研究对小梁切除术后的眼压(IOP)及并发症进行了为期5年的回顾性分析。

材料与方法

使用5mg/ml的5-氟尿嘧啶进行小梁切除术。采用温和的透热疗法止血。使用巩膜厚度的刀片碎片,制作一个4×3mm的矩形巩膜瓣。将瓣的中央部分切入透明角膜1mm。在缝线拆除前,患者局部应用0.05%地塞米松每日4次、1%阿托品每日3次、0.3%环丙沙星每日4次,持续4 - 6周。疼痛患者给予止痛剂,所有畏光患者给予防晒措施。手术成功的定义为术后眼压≤20mmHg。

结果

在5年的研究期内共有161例患者,男性占总数的70.2%。在接受手术的275只眼中,82.9%为双侧病例,17.1%为单侧病例。青光眼在11 - 82岁的儿童和成人中均有发现。然而,观察到在51 - 60岁之间最为常见,男性发病率最高。术前平均眼压为24.37mmHg,术后为15.24mmHg。排名最高的并发症是由于滤过过度导致的浅前房(24例;8.73%),其次是滤过泡渗漏(8例;2.91%)。最常见的晚期并发症是白内障(32例;11.64%)和纤维化滤过泡(8例;2.91%)。双侧白内障平均在小梁切除术后25个月发生。在2 - 3岁的患者中出现9例,而5年后,77例患者视力改善,术后视力为6/18 - 6/6。

结论

术后,由于术前眼压降低,患者获得了满意的手术效果。虽然出现了术后并发症,但它们是暂时的且不威胁视力,因此对手术效果没有影响。根据我们的经验,小梁切除术是控制眼压的一种有效且安全的手术方法。

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