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[儿童消化道某些疾病中牛奶及奶制品摄入量的测定及其与乳糖吸收不良或乳糖不耐受的关系]

[Determination of milk and diary products consumption and their connection with lactose malabsorption or lactose intolerance in selected disorders of the alimentary tract in children].

作者信息

Hutyra Tomasz, Iwańczak Barbara

机构信息

Medical University of Wrocław, Department of Pediatrics, Poland.

出版信息

Pol Merkur Lekarski. 2009 Feb;26(152):110-6.


DOI:
PMID:19388514
Abstract

UNLABELLED: Lactose stimulates proliferation and colonization of acidophilic bacteria, which due to fermentation processes lower colonic pH and simplified absorption of some microelements from the intestine. However, the common problem in children is intolerance of this carbohydrate. Treatment, quite simple, is based on partial or total elimination of lactose from diet. Some substitutional products with equivalent nutritional value should be introduced to prevent deficiencies symptoms during lactose-free diet. THE AIM OF THIS STUDY: Determination of milk and dairy products consumption and their connection with lactose malabsorption or lactose intolerance in children above 5 years of age in selected disorders of the alimentary tract: food allergy, celiac disease, secondary enteropathy, functional dyspepsia, irritable bowel syndrome and deficiency of body weight and height. MATERIAL AND METHODS: The number of 301 patients above 5 years of age (135 boys and 166 girls; mean age 11.5 years) were included into the study. Milk and dairy products consumption habits, lactose intolerance symptoms, hydrogen breath test, activity of lactase and villous atrophy were investigated. RESULTS: Decreased sweet milk consumption from, 33.33% in children with food allergy to 55.38% in children with functional indigestion was observed, in spite of gastrointestinal complaints after ingestion of milk. The biggest lactose malabsorption and lactose intolerance frequency was observed in children with decreased sweet milk consumption due to complaints after ingestion of milk and in children who didn't drink milk. There were no statistically significant difference between frequency of lactose malabsorption and lactose intolerance symptoms in children with different dairy products consumption habits. There were no statistically significant difference between frequency of hypolactasia in children with different sweet milk or dairy products consumption habits. CONCLUSIONS: Frequent (33-55%) decreased sweet milk consumption in children in spite of clinical symptoms after ingestion of milk was observed. The biggest lactose malabsorption and lactose intolerance symptoms frequency was observed in children who didn't drink milk and in children with decreased consumption of sweet milk due to complaints after ingestion of milk. There were no statistically significant difference between frequency of lactose malabsorption and lactose intolerance in children with different dairy products consumption habits.

摘要

未标注:乳糖可刺激嗜酸菌的增殖与定植,嗜酸菌通过发酵过程降低结肠pH值,并简化肠道对某些微量元素的吸收。然而,儿童中常见的问题是对这种碳水化合物不耐受。治疗方法相当简单,基于从饮食中部分或完全消除乳糖。应引入一些具有同等营养价值的替代产品,以预防无乳糖饮食期间出现缺乏症状。 本研究的目的:确定5岁以上患有某些消化道疾病(食物过敏、乳糜泻、继发性肠病、功能性消化不良、肠易激综合征以及体重和身高不足)的儿童的牛奶及奶制品摄入量及其与乳糖吸收不良或乳糖不耐受的关系。 材料与方法:301名5岁以上患者(135名男孩和166名女孩;平均年龄11.5岁)纳入研究。调查了牛奶及奶制品的消费习惯、乳糖不耐受症状、呼气氢试验、乳糖酶活性和绒毛萎缩情况。 结果:尽管摄入牛奶后有胃肠道不适症状,但观察到食物过敏儿童的甜牛奶摄入量从33.33%下降到功能性消化不良儿童的55.38%。在因摄入牛奶后不适而甜牛奶摄入量减少的儿童以及不喝牛奶的儿童中,观察到最大的乳糖吸收不良和乳糖不耐受频率。不同奶制品消费习惯的儿童中,乳糖吸收不良和乳糖不耐受症状的频率无统计学显著差异。不同甜牛奶或奶制品消费习惯的儿童中,乳糖酶缺乏的频率无统计学显著差异。 结论:尽管摄入牛奶后有临床症状,但仍观察到儿童中甜牛奶摄入量频繁(33 - 55%)下降。在不喝牛奶的儿童以及因摄入牛奶后不适而甜牛奶摄入量减少的儿童中,观察到最大的乳糖吸收不良和乳糖不耐受症状频率。不同奶制品消费习惯的儿童中,乳糖吸收不良和乳糖不耐受的频率无统计学显著差异。

相似文献

[1]
[Determination of milk and diary products consumption and their connection with lactose malabsorption or lactose intolerance in selected disorders of the alimentary tract in children].

Pol Merkur Lekarski. 2009-2

[2]
[Determination of lactose intolerance frequency in children with food allergy].

Pol Merkur Lekarski. 2008-10

[3]
Prevalence of Lactose Malabsorption and Lactose Intolerance in Pediatric Patients with Selected Gastrointestinal Diseases.

Adv Clin Exp Med. 2015

[4]
Lactose malabsorption, irritable bowel syndrome and self-reported milk intolerance.

Dig Liver Dis. 2001-4

[5]
[Relationship between primary lactose malabsorption and consumption of dairy products].

An Esp Pediatr. 1993-2

[6]
When to suspect lactose intolerance. Symptomatic, ethnic, and laboratory clues.

Postgrad Med. 1998-9

[7]
Lactose intolerance in Indonesian children.

Asia Pac J Clin Nutr. 2015

[8]
Lactose Intolerance in Adults: Biological Mechanism and Dietary Management.

Nutrients. 2015-9-18

[9]
Milk intolerance and microbe-containing dairy foods.

J Dairy Sci. 1987-2

[10]
Lactose intolerance: a non-allergic disorder often managed by allergologists.

Eur Ann Allergy Clin Immunol. 2009-2

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