Burns Jane C
Department of Pediatrics, UCSD School of Medicine, Rady Children's Hospital, La Jolla, CA 92093, USA.
Indian J Pediatr. 2009 Jan;76(1):71-6. doi: 10.1007/s12098-009-0031-3. Epub 2009 Apr 18.
Kawasaki Disease is rapidly becoming the most common cause of acquired heart disease in children in both the developed and developing world. Its etiology remains a mystery but important progress has been made in characterizing the features of the arterial wall and myocardial pathology and long-term clinical consequences. New treatments aimed at modifying the host immune response are currently under study. The genetic influence on susceptibility and disease outcome is an area of active research.
川崎病正迅速成为发达国家和发展中国家儿童后天性心脏病的最常见病因。其病因仍是个谜,但在动脉壁特征、心肌病理学以及长期临床后果的研究方面已取得重要进展。目前正在研究旨在改变宿主免疫反应的新疗法。对易感性和疾病结局的遗传影响是一个活跃的研究领域。