日本川崎病的流行病学特征：2005 - 2006年全国性调查结果
Epidemiologic features of Kawasaki disease in Japan: results from the nationwide survey in 2005-2006.
作者信息
Nakamura Yosikazu, Yashiro Mayumi, Uehara Ritei, Oki Izumi, Watanabe Makoto, Yanagawa Hiroshi
机构信息
Department of Public Health, Jichi Medical University, Shimotsuke, Tochigi, Japan.
出版信息
J Epidemiol. 2008;18(4):167-72. doi: 10.2188/jea.je2008001. Epub 2008 Jul 18.
BACKGROUND
The most recent epidemiologic features of Kawasaki disease are unknown.
METHODS
The 19th nationwide survey of the disease was conducted in 2007, targeting patients who were affected by this disease in 2005 and 2006. All pediatric departments in hospitals with 100 or more beds and pediatric hospitals were asked to report all Kawasaki disease patients during the 2 survey years.
RESULTS
From 1543 departments and hospitals, a total of 20475 patients (10041 in 2005 and 10434 in 2006) were reported. There were 11892 male patients and 8583 female patients. The average annual incidence rate was 184.6 per 100000 children aged 0-4 years. The number of patients and the incidence rate have increased significantly during the past 12 years. The age-specific incidence rate was distributed monomodally with a peak at 6-8 months of age. The prevalence of cardiac lesions in the acute phase of the disease and of cardiac sequelae were higher among infants and old patients.
CONCLUSION
The number of patients with Kawasaki disease and its incidence rate in Japan are continuously increasing.
背景
川崎病的最新流行病学特征尚不清楚。
方法
2007年开展了第19次全国性该疾病调查，目标是2005年和2006年受该疾病影响的患者。要求所有拥有100张或更多床位的医院的儿科部门以及儿童医院报告这两个调查年份期间的所有川崎病患者。
结果
来自1543个部门和医院，共报告了20475例患者（2005年为10041例，2006年为10434例）。有11892例男性患者和8583例女性患者。0至4岁儿童的年均发病率为每10万人184.6例。在过去12年中，患者数量和发病率显著增加。年龄别发病率呈单峰分布，在6至8个月龄时达到峰值。疾病急性期心脏病变和心脏后遗症的患病率在婴儿和老年患者中较高。
结论
日本川崎病患者数量及其发病率持续上升。
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