药物诱导睡眠内镜检查的重测信度
Test-retest reliability of drug-induced sleep endoscopy.
作者信息
Rodriguez-Bruno Krista, Goldberg Andrew N, McCulloch Charles E, Kezirian Eric J
机构信息
Department of Otolaryngology-Head and Neck Surgery, University of California, San Francisco, CA, USA.
出版信息
Otolaryngol Head Neck Surg. 2009 May;140(5):646-51. doi: 10.1016/j.otohns.2009.01.012.
OBJECTIVE
To determine the test-retest reliability of drug-induced sleep endoscopy (DISE).
METHODS
Prospective cohort study. Patients with OSA underwent two separate DISE examinations. The following outcomes were measured: a global assessment of obstruction at the palate and/or hypopharynx; the degree of obstruction at the palate and hypopharynx; and the contribution of individual structures (palate, tonsils, tongue, epiglottis, and lateral pharyngeal walls) to obstruction.
RESULTS
Thirty-two patients underwent two separate DISE examinations. The preoperative sleep study apnea-hypopnea index was 40.7 +/- 21.1, and the lowest oxygen saturation was 79.8 +/- 17.4 percent. Point estimates for the intraclass correlation coefficient analogs related to palatal obstruction ranged from 0.41 to 0.89; related to the hypopharyngeal airway, the point estimates ranged from 0.57 to 0.84.
CONCLUSION
The test-retest reliability of DISE appears good, especially in the evaluation of the hypopharyngeal airway. Larger studies can generate more precise confidence interval estimates and test the generalizability of these findings.
目的
确定药物诱导睡眠内镜检查（DISE）的重测信度。
方法
前瞻性队列研究。阻塞性睡眠呼吸暂停（OSA）患者接受两次独立的DISE检查。测量以下结果：腭部和/或下咽阻塞的整体评估；腭部和下咽的阻塞程度；以及各个结构（腭部、扁桃体、舌头、会厌和咽侧壁）对阻塞的影响。
结果
32例患者接受了两次独立的DISE检查。术前睡眠研究的呼吸暂停低通气指数为40.7±21.1，最低血氧饱和度为79.8±17.4%。与腭部阻塞相关的组内相关系数类似物的点估计值范围为0.41至0.89；与下咽气道相关的点估计值范围为0.57至0.84。
结论
DISE的重测信度似乎良好，尤其是在下咽气道评估方面。更大规模的研究可以生成更精确的置信区间估计，并检验这些发现的普遍性。
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