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在重度抑郁发作期间,更高的心理痛苦可能是易产生自杀意念和行为的脆弱性因素。

Higher psychological pain during a major depressive episode may be a factor of vulnerability to suicidal ideation and act.

机构信息

Université Montpellier 1, Montpellier, France.

出版信息

J Affect Disord. 2010 Jan;120(1-3):226-30. doi: 10.1016/j.jad.2009.03.013.

DOI:10.1016/j.jad.2009.03.013
PMID:19394086
Abstract

BACKGROUND

It has been suggested that psychological pain ("psychache") is a key factor in the suicidal process. In addition, suicidal acts may be best understood within a stress-vulnerability model. We hypothesized that more intense psychache during a major depressive episode would be a factor of vulnerability to suicidal behavior.

METHODS

Patients hospitalized for a major depressive episode, including 87 individuals with a recent history of suicidal acts, 61 individuals with a past history of suicidal acts, and 62 individuals without any suicidal history, were assessed at admission using several Visual Analog scales to measure levels of psychache, physical pain and suicidal ideation.

RESULTS

Patients with a recent or past history of suicide attempts expressed significantly higher levels of current psychological pain, and a higher intensity and frequency of current suicidal ideation than patients without any history of suicidal acts. The level of current psychache was significantly and positively associated with intensity and frequency of suicidal ideation. There were no between-group differences for physical pain.

LIMITATIONS

Medication status was not controlled. A lack of statistical power may have masked an association between physical pain and suicidal ideation.

CONCLUSIONS

Higher psychological pain during a major depressive episode may be a factor of vulnerability to suicidal behavior, by increasing the propensity to suicidal ideation. Measuring and taking care of psychache during a depressive episode should be a major therapeutic target during crisis intervention.

摘要

背景

有人认为心理痛苦(“psychache”)是自杀过程中的一个关键因素。此外,自杀行为可以更好地理解为一种应激易损性模型。我们假设在重度抑郁发作期间,更强烈的心理痛苦会成为易发生自杀行为的一个因素。

方法

对因重度抑郁发作住院的患者进行评估,包括 87 名有近期自杀行为史的个体、61 名有过去自杀行为史的个体和 62 名无任何自杀史的个体,在入院时使用几种视觉模拟量表来测量心理痛苦、身体疼痛和自杀意念的程度。

结果

有近期或过去自杀企图史的患者表达了更高水平的当前心理痛苦,以及更高强度和频率的当前自杀意念,与无任何自杀史的患者相比。当前心理痛苦的程度与自杀意念的强度和频率呈显著正相关。身体疼痛在组间无差异。

局限性

未控制药物状态。可能由于统计效力不足而掩盖了身体疼痛与自杀意念之间的关联。

结论

在重度抑郁发作期间,更高的心理痛苦可能是易发生自杀行为的一个因素,增加了自杀意念的倾向。在危机干预期间,测量和关注抑郁发作期间的心理痛苦应成为主要治疗目标。

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