Pasquini Massimo, Sarubbi Salvatore, Rogante Elena, Maraone Annalisa, Pinucci Irene, Boccardi Flavia, di Girolamo Paola, Berardelli Isabella, Innamorati Marco, Pompili Maurizio
Department of Human Neurosciences, Sapienza University of Rome, Rome, Italy.
Department of Neurosciences, Mental Health, and Sensory Organs, Faculty of Medicine and Psychology, Suicide Prevention Centre, Sant'Andrea Hospital, Sapienza University of Rome, Rome, Italy.
Eat Weight Disord. 2025 Jul 21;30(1):57. doi: 10.1007/s40519-025-01768-7.
Patients with eating disorders show an elevated suicide risk compared to the general population. Adverse childhood experiences, depressive symptoms, and mental pain, often accompanied by hopelessness and demoralization, may increase this risk. This study aims to explore suicidal ideation and self-injurious behaviors in a heterogeneous sample of ED patients, and their association with childhood trauma and negative mental states.
101 female patients were recruited from the inpatient and day hospital ED units at Policlinico Umberto I, Rome. Assessments included comorbid psychiatric diagnosis, suicide risk, mental pain, childhood trauma, depressive symptoms, hopelessness, and demoralization.
Suicidal ideation in the past month was significantly associated with trait and state-level mental pain, self-reported sexual abuse, depression, hopelessness, and loss of meaning. In the multivariate model, only childhood sexual abuse and loss of meaning remained significantly associated. Self-injurious behaviors in the past 3 months were associated with trait-level psychache, self-reported sexual and physical abuse, and depression severity, however significantly associated with self-injurious behaviors in the multivariate model.
Findings highlight the importance of assessing childhood trauma, especially sexual abuse, a low sense of meaning in life, depressive symptoms, and psychache in patients with EDs to improve suicide prevention strategies with specific interventions. Level of evidence III-Evidence obtained from well-designed cohort or case-control analytic studies.
与普通人群相比，饮食失调患者的自杀风险更高。不良童年经历、抑郁症状和精神痛苦，通常伴有绝望和士气低落，可能会增加这种风险。本研究旨在探讨饮食失调患者异质性样本中的自杀意念和自伤行为，以及它们与童年创伤和负面心理状态的关联。
从罗马翁贝托一世综合医院的住院部和日间医院饮食失调科室招募了101名女性患者。评估内容包括共病精神科诊断、自杀风险、精神痛苦、童年创伤、抑郁症状、绝望和士气低落。
过去一个月内的自杀意念与特质和状态层面的精神痛苦、自我报告的性虐待、抑郁、绝望和意义丧失显著相关。在多变量模型中，只有童年性虐待和意义丧失仍然显著相关。过去3个月内的自伤行为与特质层面的精神痛苦、自我报告的性虐待和身体虐待以及抑郁严重程度相关，但在多变量模型中与自伤行为显著相关。
研究结果强调了评估饮食失调患者童年创伤的重要性，尤其是性虐待、生活意义感低、抑郁症状和精神痛苦，以便通过特定干预措施改进自杀预防策略。证据级别III——从设计良好的队列研究或病例对照分析研究中获得的证据。
