美因茨TRIGA反应堆的辐照设施用于治疗肝转移瘤。

Irradiation facility at the TRIGA Mainz for treatment of liver metastases.

作者信息

Hampel G, Wortmann B, Blaickner M, Knorr J, Kratz J V, Lizón Aguilar A, Minouchehr S, Nagels S, Otto G, Schmidberger H, Schütz C, Vogtländer L

机构信息

Institut für Kernchemie, Johannes Gutenberg-Universität Mainz, Fritz-Strassmann-Weg 2, D-55128 Mainz, Germany.

出版信息

Appl Radiat Isot. 2009 Jul;67(7-8 Suppl):S238-41. doi: 10.1016/j.apradiso.2009.03.079. Epub 2009 Mar 27.

DOI:10.1016/j.apradiso.2009.03.079

PMID:19394836

Abstract

The TRIGA Mark II reactor at the University of Mainz provides ideal conditions for duplicating BNCT treatment as performed in Pavia, Italy, in 2001 and 2003 [Pinelli, T., Zonta, A., Altieri, S., Barni, S., Braghieri, A., Pedroni, P., Bruschi, P., Chiari, P., Ferrari, C., Fossati, F., Nano, R., Ngnitejeu Tata, S., Prati, U., Ricevuti, G., Roveda, L., Zonta, C., 2002. TAOrMINA: from the first idea to the application to the human liver. In: Sauerwein et al. (Eds.), Research and Development in Neutron Capture Therapy. Proceedings of the 10th International Congress on Neutron Capture Therapy, Monduzzi editore, Bologna, pp. 1065-1072]. In order to determine the optimal parameters for the planned therapy and therefore for the design of the thermal column, calculations were conducted using the MCNP-code and the transport code ATTILA. The results of the parameter study as well as a possible configuration for the irradiation of the liver are presented.

摘要

美因茨大学的TRIGA Mark II反应堆为复制2001年和2003年在意大利帕维亚进行的硼中子俘获疗法（BNCT）治疗提供了理想条件[皮内利，T.，宗塔，A.，阿尔蒂耶里，S.，巴尔尼，S.，布拉吉耶里，A.，佩德罗尼，P.，布鲁斯基，P.，基亚里，P.，法拉利，C.，福萨蒂，F.，纳诺，R.，恩尼泰杰乌·塔塔，S.，普拉蒂，U.，里塞武蒂，G.，罗韦达，L.，宗塔，C.，2002年。陶尔米纳：从最初的想法到应用于人类肝脏。载于：绍尔韦因等人（编）。中子俘获疗法的研究与开发。第10届国际中子俘获疗法大会论文集，蒙杜齐出版社，博洛尼亚，第1065 - 1072页]。为了确定计划治疗的最佳参数，从而确定热柱的设计参数，使用MCNP代码和传输代码ATTILA进行了计算。本文展示了参数研究的结果以及肝脏照射的一种可能配置。