Martin D J, Oren Z, Boone K
Department of Psychiatry, Harbor-UCLA Medical Center, Torrance 90509.
J Clin Psychol. 1991 Sep;47(5):684-90. doi: 10.1002/1097-4679(199109)47:5<684::aid-jclp2270470509>3.0.co;2-g.
Despite awareness that depression may affect performance on commonly used neuropsychological tests, little research has been conducted on the relative impact of severity and type of depression on higher problem-solving ability. Major depressives (n = 13), dysthymics (n = 17), and non-psychiatric comparison subjects (n = 18) were administered the Wisconsin Card Sorting Test (WCST). Although diagnostic category was related only marginally to some WCST measures after controlling for intellectual function, depressive symptom severity emerged as an independent predictor of Total Errors, Perseverative Responses, and Failure to Maintain Set. These findings lend support to the suggestion that neuropsychological test batteries should include assessment for depression and suggest that even relatively mild depression may affect WCST scores.
尽管人们已经认识到抑郁症可能会影响常用神经心理学测试的表现，但关于抑郁症的严重程度和类型对更高层次解决问题能力的相对影响，所开展的研究却很少。对13名重度抑郁症患者、17名心境恶劣障碍患者和18名非精神科对照受试者进行了威斯康星卡片分类测验（WCST）。尽管在控制了智力功能后，诊断类别仅与某些WCST指标存在微弱关联，但抑郁症状严重程度却成为总错误数、持续性反应以及无法维持定势的独立预测因素。这些发现支持了以下建议，即神经心理学测试组合应包括对抑郁症的评估，并表明即使是相对轻度的抑郁症也可能影响WCST分数。
