Zhang Jianmin, Ciufolini Marco A
Department of Chemistry, University of British Columbia, 2036 Main Mall, Vancouver BC V6T 1Z1, Canada.
Org Lett. 2009 Jun 4;11(11):2389-92. doi: 10.1021/ol900455m.
The preparation of 4-carbethoxy-5-methyl-2-(phenylsulfonyl)methyloxazole and its use in the elaboration of more complex oxazoles are described. A total synthesis of the unique natural products, siphonazoles A and B, illustrates an application of the new building block.
描述了4-乙氧羰基-5-甲基-2-(苯磺酰基)甲基恶唑的制备及其在更复杂恶唑合成中的应用。独特天然产物西弗恶唑A和B的全合成说明了这种新构建模块的一种应用。