Alster Tina S, Wanitphakdeedecha Rungsima
Washington Institute of Dermatologic Laser Surgery, District of Columbia, USA.
Dermatol Surg. 2009 May;35(5):813-5. doi: 10.1111/j.1524-4725.2009.01137.x. Epub 2009 Apr 6.
The most common side effects of fractional laser skin treatment are erythema and edema. Low-level light therapy and light-emitting diode (LED) devices have been used to stimulate fibroblast activity and hasten wound healing.
To determine whether LED treatment immediately after fractional laser skin resurfacing affects the severity and duration of postoperative eythema.
Twenty patients received treatment with a 590-nm wavelength LED array to randomly selected facial halves immediately after undergoing full-face fractional laser skin resurfacing with a 1,550-nm erbium-doped fiber laser. Differences in erythema between LED-treated and untreated facial halves were recorded at 24, 48, and 96 hours post-treatment.
The LED-treated facial halves were less erythematous in all 20 patients 24 hours postoperatively. The six patients who received the highest mean energy densities during fractional laser treatment continued to exhibit decreased erythema in the LED-treated areas at 48 hours. At 96 hours post-treatment, no discernible differences between facial halves were observed in any patient.
Photomodulation with a 590-nm-wavelength LED array can decrease the intensity and duration of postfractional laser treatment erythema.
点阵激光皮肤治疗最常见的副作用是红斑和水肿。低强度光疗法及发光二极管(LED)设备已被用于刺激成纤维细胞活性并加速伤口愈合。
确定点阵激光皮肤磨削术后立即进行LED治疗是否会影响术后红斑的严重程度和持续时间。
20例患者在使用1550纳米掺铒光纤激光进行全脸点阵激光皮肤磨削术后,立即用590纳米波长的LED阵列对随机选择的半侧面部进行治疗。在治疗后24、48和96小时记录LED治疗侧与未治疗侧面部红斑的差异。
所有20例患者术后24小时,接受LED治疗的半侧面部红斑较轻。在点阵激光治疗期间接受平均能量密度最高的6例患者,在48小时时LED治疗区域的红斑持续减轻。治疗后96小时,未观察到任何患者两侧面部有明显差异。
使用590纳米波长的LED阵列进行光调制可降低点阵激光治疗后红斑的强度和持续时间。