Trelles Mario A, Allones Inés
Instituto Médico Vilafortuny/Antoni de Gimbernat Foundation, Cambrils, Spain.
J Cosmet Laser Ther. 2006 Apr;8(1):39-42. doi: 10.1080/14764170600607731.
Blepharoplasties can be associated with sequelae-related patient downtime, often extended or reinforced by periocular laser ablative resurfacing. The present controlled study examined the effects of a new-generation LED phototherapy system on enhancing wound healing following such combination surgery.
Two males and eight females participated in the trial, with ages ranging from 44 to 59 years (average 52.3 years). Following blepharoplasty and Er:YAG/CO2 laser ablative resurfacing, one-half of each subject's face was treated with the red LED therapy (20 min, 96 J/cm2, 633 nm), the contralateral half being the unirradiated control. Patients reported subjectively on pain levels and resolution. Resolution of erythema, edema, bruising and days to healing were independently evaluated from the clinical photography. All findings were compared between the treated and untreated sides.
In all instances, the LED therapy-treated side was statistically significantly superior to the unirradiated control by a factor of two to three.
In this small series of 10 patients, red LED phototherapy after blepharoplasty and laser ablative resurfacing cut the time to resolution of side effects and the healing time by one-half to one-third compared with contralateral unirradiated controls. Further studies are warranted with larger populations to confirm these findings.
眼睑成形术可能会导致与后遗症相关的患者停工期,而眼周激光消融换肤术往往会延长或加剧这种情况。本对照研究探讨了新一代LED光疗系统对这种联合手术后促进伤口愈合的效果。
两名男性和八名女性参与了该试验,年龄在44至59岁之间(平均52.3岁)。在进行眼睑成形术和铒激光/二氧化碳激光消融换肤术后,每位受试者脸部的一半接受红色LED疗法治疗(20分钟,96焦耳/平方厘米,633纳米),对侧脸部作为未照射的对照。患者主观报告疼痛程度和恢复情况。从临床照片中独立评估红斑、水肿、瘀伤的消退情况以及愈合天数。对治疗侧和未治疗侧的所有结果进行比较。
在所有情况下,接受LED疗法治疗的一侧在统计学上比未照射的对照侧显著优越两到三倍。
在这一小系列的10名患者中,与对侧未照射的对照相比,眼睑成形术和激光消融换肤术后的红色LED光疗将副作用的消退时间和愈合时间缩短了二分之一到三分之一。有必要对更多人群进行进一步研究以证实这些发现。