Fleck Tatjana, Fleck Michael, Müller Michael, Hager Helmut, Klepetko Walter, Wolner Ernst, Wisser Wilfried
Department of Cardiothoracic Surgery, Medical University of Vienna, AKH Vienna, Vienna, Austria.
Interact Cardiovasc Thorac Surg. 2009 Nov;9(5):784-7. doi: 10.1510/icvts.2009.202531. Epub 2009 Apr 28.
Surgical treatment of myasthenia gravis should include the complete resection of the thymus with the whole fatty tissue adherent to the pericardium for immunologic as well as oncologic reasons. The aim of the current study was to investigate the efficacy and safety of robotic approach. A total of 18 patients with myasthenia gravis (mean age 44 years) have been operated robotically via a left-sided approach. Preoperative MGFA (Myasthenia Gravis Foundation of America) classification was: Class I n=4, Class IIa n=4, Class IIb n=5, and Class IIIa n=3, IIIb n=2. Total endoscopic resection was feasible in 17/18 patients. One patient had to be converted due to bleeding. In the remaining patients, operative time was 175 min, intensive care unit (ICU) one day, hospital stay four days. In all patients it was possible to perform an extended thymic resection. MGFA post-intervention status after a mean of 18 months follow-up showed complete stable remission n=5, pharmacologic remission n=4, minimal manifestations n=5, unchanged n=1. Complete endoscopic thymus surgery with the da Vinci surgical system enables a complete and extended resection of all thymic tissue in the mediastinum. Due to the minimal trauma, patients can return to full activity within a short time.
出于免疫学和肿瘤学原因,重症肌无力的外科治疗应包括完整切除胸腺及附着于心包的全部脂肪组织。本研究的目的是探讨机器人手术方法的疗效和安全性。共有18例重症肌无力患者(平均年龄44岁)接受了左侧入路的机器人手术。术前美国重症肌无力基金会(MGFA)分级为:I级4例,IIa级4例,IIb级5例,IIIa级3例,IIIb级2例。18例患者中有17例可行全内镜下切除。1例患者因出血而中转开胸。其余患者手术时间为175分钟,重症监护病房(ICU)住院1天,住院时间4天。所有患者均可行扩大胸腺切除术。平均随访18个月后的MGFA干预后状态显示完全稳定缓解5例,药物缓解4例,轻度表现5例,无变化1例。使用达芬奇手术系统进行全内镜下胸腺手术能够完整、扩大切除纵隔内所有胸腺组织。由于创伤极小,患者可在短时间内恢复正常活动。