Donat J F, Wright F S
Department of Pediatrics, Children's Hospital, Ohio State University School of Medicine, Columbus 43205.
J Child Neurol. 1991 Oct;6(4):313-8. doi: 10.1177/088307389100600405.
During evaluation of video-electroencephalograms (EEGs) performed in our laboratory, we identified 11 patients who had unusual repetitive movements that appeared to be variants of infantile spasms. Movements included yawning, facial grimacing, eye movements, and transient focal motor activity. These symptoms coincided with generalized attenuation, slow-wave transients, or other EEG ictal changes characteristic of infantile spasms. The background EEGs showed true or modified hypsarrhythmia. This series of patients shows that infantile spasms may be extremely subtle and clinically atypical. Patients who have these variants may or may not also have typical infantile spasms. In some patients, the seizures appear to be time-related or medication-induced modifications of more typical infantile spasms.
在对我们实验室进行的视频脑电图（EEG）评估过程中，我们识别出11例患者，他们有不寻常的重复性动作，这些动作似乎是婴儿痉挛症的变体。动作包括打哈欠、面部 grimacing、眼球运动和短暂的局灶性运动活动。这些症状与婴儿痉挛症特征性的广泛性衰减、慢波瞬变或其他脑电图发作期变化同时出现。背景脑电图显示为真性或改良型高峰失律。这一系列患者表明，婴儿痉挛症可能极其细微且临床上不典型。有这些变体的患者可能有也可能没有典型的婴儿痉挛症。在一些患者中，癫痫发作似乎是与时间相关或药物诱发的更典型婴儿痉挛症的改变。
