King D W, Dyken P R, Spinks I L, Murvin A J
Department of Neurology; Medical College of Georgia, Augusta 30912.
Pediatr Neurol. 1985 Jul-Aug;1(4):213-8. doi: 10.1016/s0887-8994(85)80002-3.
Ictal phenomena were studied during three separate six-hour video/polygraphic recording sessions in 10 patients with infantile spasms; 1,079 spasms occurred. Frequency during wakefulness (7.7 spasms/hour) was greater than that during sleep (2.5 spasms/hour); 46.6% of spasms occurred in clusters. Spasms were composed of one or more of three phases: a myoclonic contraction, a tonic contraction, and/or an arrest of activity. The most common types were myoclonic-tonic (40.3%) and myoclonic alone (36.3%). When classified by postural motor phenomena, 41.6% were "flexor", 16.3% "extensor", 39.0% "mixed", and 3.1% "arrest" alone. Electrographic monitoring revealed that myoclonic contractions were associated with an initial paroxysmal event. Tonic contractions and arrests were usually associated with suppression of electroencephalographic activity with or without rhythmic activity. Knowledge of these clinical and electrographic features is important for diagnosis and evaluation of proposed treatments.
在对10例婴儿痉挛症患者进行的三次独立的六小时视频/多导记录过程中，对发作期现象进行了研究；共发生1079次痉挛。清醒时的发作频率（7.7次痉挛/小时）高于睡眠时（2.5次痉挛/小时）；46.6%的痉挛呈簇状发作。痉挛由三个阶段中的一个或多个组成：肌阵挛性收缩、强直性收缩和/或活动停止。最常见的类型是肌阵挛-强直性（40.3%）和单纯肌阵挛（36.3%）。按姿势运动现象分类时，41.6%为“屈曲型”，16.3%为“伸展型”，39.0%为“混合型”，3.1%为单纯“静止型”。脑电图监测显示，肌阵挛性收缩与最初的阵发性事件相关。强直性收缩和活动停止通常与脑电图活动的抑制有关，无论有无节律性活动。了解这些临床和脑电图特征对于诊断和评估所提议的治疗方法很重要。
