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阿尔弗雷德·弗朗索瓦·多内(1801 - 1878):显微镜学、微生物学和血液学的先驱。

Alfred Francois Donné (1801-78): a pioneer of microscopy, microbiology and haematology.

作者信息

Diamantis Aristidis, Magiorkinis Emmanouil, Androutsos George

机构信息

Department of Cytopathology in Naval Hospital of Athens and Office for the Study of the History of Hellenic Naval Medicine, Athens, Greece.

出版信息

J Med Biogr. 2009 May;17(2):81-7. doi: 10.1258/jmb.2008.008040.

Abstract

Alfred François Donné is widely known in the scientific community as the discoverer of Trichomonas vaginalis, since he was the first to illustrate the parasite that later was recognized to cause vaginal infections. However, his other, less-known findings are equally important: he was also the inventor of the photoelectric microscope, with the assistance of his student Léon Foucault, as well as the first to apply photography to microscopic preparations (Daguerreotype). His research in microscopy extended to almost all human fluids that could be investigated and culminated in his famous Atlas, which was illustrated with numerous photographs. Donné was also the first to describe the microscopic appearances of leukaemia based on blood preparations acquired from patients. Finally, his work in the hygiene of child upbringing and nutrition is very significant.

摘要

阿尔弗雷德·弗朗索瓦·多内作为阴道毛滴虫的发现者在科学界广为人知,因为他是第一个描绘出这种后来被认为会引发阴道感染的寄生虫的人。然而,他的其他鲜为人知的发现同样重要:在他的学生莱昂·傅科的协助下,他还是光电显微镜的发明者,并且是第一个将摄影技术应用于显微标本制作(达盖尔银版照相法)的人。他在显微镜学方面的研究几乎涵盖了所有可研究的人体体液,并最终形成了他著名的图谱集,其中配有大量照片。多内也是第一个根据从患者身上采集的血液标本描述白血病微观表现的人。最后,他在儿童养育和营养卫生方面的工作意义重大。

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