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头颈部癌症的开放性颈淋巴结活检:有任何益处吗?

Open cervical lymph node biopsy for head and neck cancers: any benefit?

作者信息

Adoga Adeyi A, Silas Olugbenga A, Nimkur Tonga L

机构信息

Otorhinolaryngology Unit, Department of surgery, Jos University Teaching Hospital, PMB 2076, Jos, Plateau state, Nigeria.

出版信息

Head Neck Oncol. 2009 Apr 29;1:9. doi: 10.1186/1758-3284-1-9.

Abstract

BACKGROUND

Most patients with head and neck cancers in our environment present late and usually first to the general surgeons whose practice is to subject these patients to open cervical lymph node biopsy without a prior examination under anesthesia and endoscopic biopsy from the primary tumor site in order to obtain a histological diagnosis. This paper presents the influence of open cervical lymph node biopsy on the clinical outcome of patients with head and neck cancers in our environment.

METHODS

This is a ten-year retrospective review of patients with head and neck cancers in the Jos University Teaching Hospital, Jos, Nigeria.

RESULTS

Eighty nine patients aged between 23 and 78 years had head and neck cancers with 38/89 (42.7%) patients having cervical lymphadenopathy at presentation and these initially presented to the general surgeons. Twenty six (68.4%) patients had open cervical lymph node biopsy and 12/38 (31.6%) patients had FNAB. Eleven (28.9%) patients presented to the otolaryngology unit 6 months after they presented to the general surgeons and 27 (71.1%) patients beyond 6 months. Nine deaths were recorded. Ten patients were lost to follow-up.

CONCLUSION

All patients with head and neck lymphadenopathy who present to any physician for diagnostic examination should undergo formal ENT staging and FNAB to avoid the problems of tumor spread and the reduction in consequent prognosis.

摘要

背景

在我们所处的环境中,大多数头颈癌患者就诊时已处于疾病晚期,通常首先前往普通外科医生处就诊,这些医生的常规做法是在未进行麻醉下的预先检查及未对原发肿瘤部位进行内镜活检的情况下,对这些患者进行开放性颈部淋巴结活检,以获取组织学诊断。本文介绍了开放性颈部淋巴结活检对我们所处环境中头颈癌患者临床结局的影响。

方法

这是对尼日利亚乔斯大学教学医院的头颈癌患者进行的一项为期十年的回顾性研究。

结果

89例年龄在23岁至78岁之间的患者患有头颈癌,其中38/89(42.7%)例患者就诊时伴有颈部淋巴结病,这些患者最初前往普通外科医生处就诊。26例(68.4%)患者进行了开放性颈部淋巴结活检,12/38(31.6%)例患者进行了细针穿刺抽吸活检(FNAB)。11例(28.9%)患者在前往普通外科医生处就诊6个月后转诊至耳鼻喉科,27例(71.1%)患者在6个月之后转诊。记录到9例死亡。10例患者失访。

结论

所有因诊断性检查而就诊于任何医生的头颈淋巴结病患者均应接受正规的耳鼻喉科分期检查及细针穿刺抽吸活检,以避免肿瘤扩散问题及随之而来的预后降低。

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