Rahil Ali Ibrahim, Errayes Mehdi, Salem Khaled M
Department of medicine, Hamad General Hospital, Doha-Qatar.
Chang Gung Med J. 2009 Mar-Apr;32(2):220-3.
Neurological symptoms are rare manifestations of Behcet's disease. In this paper, we report cerebral venous thrombosis as the initial presentation of Behcet's disease in a 40 yearold man. Our patient presented with a six-week history of headache, progressive loss of vision in the right eye and recurrent oral ulcers. Physical examination revealed oral ulcers and posterior synechia in the right eye with loss of light perception. Fundoscopic examination showed evidence of retinal vasculitis. Magnetic resonance imaging (MRI) and magnetic resonance venography (MRV) of the brain showed superior sagittal, left transverse, and left sigmoid sinus venous thrombosis. A diagnosis of Behcet's disease was made based on clinical criteria. Treatment with methylpredinsolone, cyclophosphamide, and azathioprine as well as anticoagulation was done with significant clinical improvement.
神经系统症状是白塞病的罕见表现。在本文中，我们报告了一名40岁男性以脑静脉血栓形成作为白塞病的首发表现。我们的患者有六周的头痛病史、右眼视力进行性丧失和复发性口腔溃疡。体格检查发现口腔溃疡以及右眼有虹膜后粘连且无光感。眼底检查显示有视网膜血管炎的迹象。脑部磁共振成像（MRI）和磁共振静脉血管造影（MRV）显示上矢状窦、左侧横窦和左侧乙状窦静脉血栓形成。根据临床标准诊断为白塞病。采用甲泼尼龙、环磷酰胺和硫唑嘌呤治疗以及抗凝治疗后，临床症状有显著改善。
