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欧洲人类生殖与胚胎学会(ESHRE)胚胎植入前基因诊断(PGD)联盟数据收集IX:2006年1月至12月周期及随访至2007年10月的妊娠情况

ESHRE PGD Consortium data collection IX: cycles from January to December 2006 with pregnancy follow-up to October 2007.

作者信息

Goossens V, Harton G, Moutou C, Traeger-Synodinos J, Van Rij M, Harper J C

机构信息

ESHRE Central Office, Meerstraat 60, 1852 Grimbergen, Belgium.

出版信息

Hum Reprod. 2009 Aug;24(8):1786-810. doi: 10.1093/humrep/dep059. Epub 2009 Apr 29.

Abstract

The ninth report of the European Society of Human Reproduction and Embryology Preimplantation Genetic Diagnosis Consortium is presented documenting cycles collected for the calendar year 2006 and follow-up of the pregnancies and babies born until October 2007, which resulted from these cycles. Since the beginning of the data collections there has been a steady increase in the number of cycles, pregnancies and babies reported annually. For data collection IX, 57 centres have participated, reporting on 5858 cycles to oocyte retrieval (OR), along with details of the follow-up on 1437 pregnancies and 1206 babies born. Eight hundred and twelve ORs were reported for chromosomal abnormalities, 133 ORs for sexing for X-linked diseases, 931 ORs for monogenic diseases, 3900 ORs for preimplantation genetic screening and 82 ORs for social sexing. Data IX are compared with the cumulative data for data collections I-VIII.

摘要

欧洲人类生殖与胚胎学会植入前基因诊断协会第九次报告公布了2006历年收集的周期情况,以及这些周期所产生的直至2007年10月出生的妊娠和婴儿的随访情况。自开始收集数据以来,每年报告的周期、妊娠和婴儿数量一直在稳步增加。对于第九次数据收集,有57个中心参与,报告了5858个取卵周期(OR),以及1437例妊娠和1206例出生婴儿的随访细节。报告了812个因染色体异常的取卵周期、133个用于X连锁疾病性别鉴定的取卵周期、931个用于单基因疾病的取卵周期、3900个用于植入前基因筛查的取卵周期和82个用于社会性别鉴定的取卵周期。将第九次数据与第一至八次数据收集的累积数据进行了比较。

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